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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACTL7B All Species: 25.45
Human Site: S306 Identified Species: 46.67
UniProt: Q9Y614 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y614 NP_006677.1 415 45234 S306 S E M L F Q P S L A G S T Q P
Chimpanzee Pan troglodytes XP_528383 415 44998 S306 S E M L F Q P S L A G S T Q P
Rhesus Macaque Macaca mulatta XP_001108601 415 45086 S306 S E M L F Q P S L A G S T Q P
Dog Lupus familis XP_538780 454 47892 S345 A E M L F R P S V A G S S Q P
Cat Felis silvestris
Mouse Mus musculus Q9QY83 418 45642 S309 S E M L F K P S L V G C T Q P
Rat Rattus norvegicus Q4QR76 417 45474 S308 S E M L F K P S L V G S T Q P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512771 444 49613 S335 A E M L F K P S V I G S K Q L
Chicken Gallus gallus
Frog Xenopus laevis P53506 376 41829 M270 F Q P S F L G M E S C G I H E
Zebra Danio Brachydanio rerio Q7ZVI7 375 41748 M269 F Q P S F L G M E S C G I H E
Tiger Blowfish Takifugu rubipres P68142 375 41748 M269 F Q P S F L G M E S C G I H E
Fruit Fly Dros. melanogaster P02572 376 41805 M270 F Q P S F L G M E A C G I H E
Honey Bee Apis mellifera XP_393368 376 41787 M270 F Q P S F L G M E A C G I H E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786731 376 41813 M270 F Q P A F V G M E A A G L H E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 97.8 68.9 N.A. 86.3 87.2 N.A. 53.3 N.A. 40.7 40.9 40.9 40.7 40.7 N.A. 40.2
Protein Similarity: 100 99.2 98.5 76.6 N.A. 91.6 92 N.A. 68.6 N.A. 57.8 59 59 57.5 57.8 N.A. 57.5
P-Site Identity: 100 100 100 73.3 N.A. 80 86.6 N.A. 60 N.A. 6.6 6.6 6.6 13.3 13.3 N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 86.6 93.3 N.A. 80 N.A. 20 20 20 20 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 0 8 0 0 0 0 0 54 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 39 8 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 54 0 0 0 0 0 0 47 0 0 0 0 0 47 % E
% Phe: 47 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 47 0 0 0 54 47 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 47 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 8 0 0 39 0 0 % I
% Lys: 0 0 0 0 0 24 0 0 0 0 0 0 8 0 0 % K
% Leu: 0 0 0 54 0 39 0 0 39 0 0 0 8 0 8 % L
% Met: 0 0 54 0 0 0 0 47 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 47 0 0 0 54 0 0 0 0 0 0 0 47 % P
% Gln: 0 47 0 0 0 24 0 0 0 0 0 0 0 54 0 % Q
% Arg: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % R
% Ser: 39 0 0 39 0 0 0 54 0 24 0 47 8 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 39 0 0 % T
% Val: 0 0 0 0 0 8 0 0 16 16 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _