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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTL7B
All Species:
23.03
Human Site:
Y281
Identified Species:
42.22
UniProt:
Q9Y614
Number Species:
12
Phosphosite Substitution
Charge Score:
0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y614
NP_006677.1
415
45234
Y281
P
E
E
L
R
V
D
Y
E
L
P
D
G
K
L
Chimpanzee
Pan troglodytes
XP_528383
415
44998
Y281
P
D
E
L
R
V
D
Y
E
L
P
D
G
K
L
Rhesus Macaque
Macaca mulatta
XP_001108601
415
45086
Y281
P
E
E
L
R
V
D
Y
E
L
P
D
G
K
L
Dog
Lupus familis
XP_538780
454
47892
Y320
E
L
G
L
R
V
D
Y
E
L
P
D
G
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9QY83
418
45642
Y284
L
D
E
L
H
V
D
Y
E
L
P
D
G
K
I
Rat
Rattus norvegicus
Q4QR76
417
45474
Y283
L
D
E
L
H
V
D
Y
E
L
P
D
G
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512771
444
49613
Y310
Y
K
N
E
V
I
D
Y
H
L
P
D
G
Q
A
Chicken
Gallus gallus
Frog
Xenopus laevis
P53506
376
41829
D245
E
K
S
Y
E
L
P
D
G
Q
V
I
T
I
G
Zebra Danio
Brachydanio rerio
Q7ZVI7
375
41748
D244
E
K
S
Y
E
L
P
D
G
Q
V
I
T
I
G
Tiger Blowfish
Takifugu rubipres
P68142
375
41748
D244
E
K
S
Y
E
L
P
D
G
Q
V
I
T
I
G
Fruit Fly
Dros. melanogaster
P02572
376
41805
D245
E
K
S
Y
E
L
P
D
G
Q
V
I
T
I
G
Honey Bee
Apis mellifera
XP_393368
376
41787
D245
E
K
S
Y
E
L
P
D
G
Q
V
I
T
I
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786731
376
41813
D245
E
K
S
Y
E
L
P
D
G
Q
I
I
T
I
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97.8
68.9
N.A.
86.3
87.2
N.A.
53.3
N.A.
40.7
40.9
40.9
40.7
40.7
N.A.
40.2
Protein Similarity:
100
99.2
98.5
76.6
N.A.
91.6
92
N.A.
68.6
N.A.
57.8
59
59
57.5
57.8
N.A.
57.5
P-Site Identity:
100
93.3
100
66.6
N.A.
73.3
73.3
N.A.
40
N.A.
0
0
0
0
0
N.A.
0
P-Site Similarity:
100
100
100
73.3
N.A.
86.6
86.6
N.A.
60
N.A.
13.3
13.3
13.3
13.3
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
24
0
0
0
0
54
47
0
0
0
54
0
0
0
% D
% Glu:
54
16
39
8
47
0
0
0
47
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
47
0
0
0
54
0
47
% G
% His:
0
0
0
0
16
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
8
47
0
47
8
% I
% Lys:
0
54
0
0
0
0
0
0
0
0
0
0
0
39
0
% K
% Leu:
16
8
0
47
0
47
0
0
0
54
0
0
0
0
24
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
24
0
0
0
0
0
47
0
0
0
54
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
47
0
0
0
8
0
% Q
% Arg:
0
0
0
0
31
0
0
0
0
0
0
0
0
8
8
% R
% Ser:
0
0
47
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
47
0
0
% T
% Val:
0
0
0
0
8
47
0
0
0
0
39
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
47
0
0
0
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _