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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTL7A
All Species:
26.67
Human Site:
S170
Identified Species:
45.13
UniProt:
Q9Y615
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y615
NP_006678.1
435
48644
S170
E
E
H
A
V
L
V
S
D
P
P
L
S
P
H
Chimpanzee
Pan troglodytes
XP_520173
435
48560
S170
E
E
H
A
V
L
V
S
D
P
P
L
S
P
H
Rhesus Macaque
Macaca mulatta
XP_001108489
435
48687
S170
E
E
H
A
V
L
V
S
D
P
P
L
S
P
H
Dog
Lupus familis
XP_532025
440
49173
S175
E
E
H
A
V
L
V
S
D
P
P
L
S
P
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9QY84
440
49432
S175
E
E
H
A
V
L
V
S
D
P
P
L
S
P
H
Rat
Rattus norvegicus
Q641W9
440
49549
S175
E
E
H
A
V
L
V
S
D
P
P
L
S
P
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512771
444
49613
S180
A
E
H
A
V
L
V
S
D
P
P
L
S
P
S
Chicken
Gallus gallus
P53478
376
41817
Q138
P
A
M
Y
V
A
I
Q
A
V
L
S
L
Y
A
Frog
Xenopus laevis
P53506
376
41829
Q138
P
A
M
Y
V
A
I
Q
A
V
L
S
L
Y
A
Zebra Danio
Brachydanio rerio
Q7ZVI7
375
41748
Q137
P
A
M
Y
V
A
I
Q
A
V
L
S
L
Y
A
Tiger Blowfish
Takifugu rubipres
P53485
375
41748
Q137
P
A
M
Y
V
A
I
Q
A
V
L
S
L
Y
A
Fruit Fly
Dros. melanogaster
P10987
376
41803
Q138
P
A
M
Y
V
A
I
Q
A
V
L
S
L
Y
A
Honey Bee
Apis mellifera
XP_393368
376
41787
Q138
P
A
M
Y
V
A
I
Q
A
V
L
S
L
Y
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786731
376
41813
Q138
P
A
M
Y
V
G
I
Q
A
V
L
S
L
Y
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98.8
86.5
N.A.
85.2
85.6
N.A.
63
38.3
38.1
38.3
38.3
38.6
38.6
N.A.
38.1
Protein Similarity:
100
99.3
98.8
91.8
N.A.
91.3
91.1
N.A.
77
57.2
57.2
57
56.5
57
57
N.A.
56
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
86.6
6.6
6.6
6.6
6.6
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
13.3
13.3
13.3
13.3
13.3
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
50
0
50
0
43
0
0
50
0
0
0
0
0
50
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% D
% Glu:
43
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
43
% H
% Ile:
0
0
0
0
0
0
50
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
50
0
0
0
0
50
50
50
0
0
% L
% Met:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
50
0
0
0
0
0
0
0
0
50
50
0
0
50
0
% P
% Gln:
0
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
50
0
0
0
50
50
0
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
100
0
50
0
0
50
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
50
0
0
0
0
0
0
0
0
0
50
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _