KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTL7A
All Species:
12.42
Human Site:
T125
Identified Species:
21.03
UniProt:
Q9Y615
Number Species:
13
Phosphosite Substitution
Charge Score:
0.54
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y615
NP_006678.1
435
48644
T125
V
G
Q
E
L
N
N
T
N
V
H
L
K
L
V
Chimpanzee
Pan troglodytes
XP_520173
435
48560
T125
V
G
Q
E
L
N
N
T
N
V
H
L
K
L
V
Rhesus Macaque
Macaca mulatta
XP_001108489
435
48687
T125
V
G
Q
E
L
N
N
T
N
V
H
L
K
L
V
Dog
Lupus familis
XP_532025
440
49173
P130
V
G
K
E
L
I
N
P
E
V
R
L
K
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9QY84
440
49432
P130
V
G
H
E
L
F
N
P
D
I
H
L
K
L
V
Rat
Rattus norvegicus
Q641W9
440
49549
P130
V
G
R
E
L
F
N
P
D
I
H
L
K
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512771
444
49613
S135
V
G
H
E
L
L
N
S
S
E
P
L
K
L
I
Chicken
Gallus gallus
P53478
376
41817
E101
E
L
R
V
A
P
E
E
H
P
V
L
L
T
E
Frog
Xenopus laevis
P53506
376
41829
E101
E
L
R
V
A
P
E
E
H
P
V
L
L
T
E
Zebra Danio
Brachydanio rerio
Q7ZVI7
375
41748
E100
E
L
R
V
A
P
E
E
H
P
V
L
L
T
E
Tiger Blowfish
Takifugu rubipres
P53485
375
41748
E100
E
L
R
V
A
P
E
E
H
P
V
L
L
T
E
Fruit Fly
Dros. melanogaster
P10987
376
41803
E101
E
L
R
V
A
P
E
E
H
P
V
L
L
T
E
Honey Bee
Apis mellifera
XP_393368
376
41787
E101
E
L
R
V
A
P
E
E
H
P
V
L
L
T
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786731
376
41813
E101
E
L
R
V
A
P
E
E
H
P
V
L
L
T
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98.8
86.5
N.A.
85.2
85.6
N.A.
63
38.3
38.1
38.3
38.3
38.6
38.6
N.A.
38.1
Protein Similarity:
100
99.3
98.8
91.8
N.A.
91.3
91.1
N.A.
77
57.2
57.2
57
56.5
57
57
N.A.
56
P-Site Identity:
100
100
100
66.6
N.A.
66.6
66.6
N.A.
53.3
6.6
6.6
6.6
6.6
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
73.3
N.A.
80
86.6
N.A.
73.3
20
20
20
20
20
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% D
% Glu:
50
0
0
50
0
0
50
50
8
8
0
0
0
0
50
% E
% Phe:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
15
0
0
0
0
0
50
0
36
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
15
0
0
0
0
8
% I
% Lys:
0
0
8
0
0
0
0
0
0
0
0
0
50
0
0
% K
% Leu:
0
50
0
0
50
8
0
0
0
0
0
100
50
50
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
22
50
0
22
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
50
0
22
0
50
8
0
0
0
0
% P
% Gln:
0
0
22
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
58
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
22
0
0
0
0
0
50
0
% T
% Val:
50
0
0
50
0
0
0
0
0
29
50
0
0
0
43
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _