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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTL7A
All Species:
26.06
Human Site:
Y244
Identified Species:
44.1
UniProt:
Q9Y615
Number Species:
13
Phosphosite Substitution
Charge Score:
0.54
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y615
NP_006678.1
435
48644
Y244
S
I
T
G
R
L
D
Y
A
G
S
D
L
T
A
Chimpanzee
Pan troglodytes
XP_520173
435
48560
Y244
S
I
T
G
R
L
D
Y
A
G
S
D
L
T
A
Rhesus Macaque
Macaca mulatta
XP_001108489
435
48687
Y244
S
I
T
G
R
L
D
Y
A
G
S
D
L
T
A
Dog
Lupus familis
XP_532025
440
49173
Y249
S
I
T
G
R
L
D
Y
A
G
S
D
L
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9QY84
440
49432
Y249
S
I
T
G
R
L
D
Y
A
G
S
D
L
T
T
Rat
Rattus norvegicus
Q641W9
440
49549
Y249
S
I
T
G
R
L
D
Y
A
G
S
D
L
T
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512771
444
49613
Y254
N
I
T
D
R
L
D
Y
A
G
S
D
V
T
L
Chicken
Gallus gallus
P53478
376
41817
D212
A
E
R
E
I
V
R
D
I
K
E
K
L
C
Y
Frog
Xenopus laevis
P53506
376
41829
D212
A
E
R
E
I
V
R
D
I
K
E
K
P
C
Y
Zebra Danio
Brachydanio rerio
Q7ZVI7
375
41748
D211
A
E
R
E
I
V
R
D
I
K
E
K
L
C
Y
Tiger Blowfish
Takifugu rubipres
P53485
375
41748
D211
A
E
R
E
I
V
R
D
I
K
E
K
L
C
Y
Fruit Fly
Dros. melanogaster
P10987
376
41803
D212
A
E
R
E
I
V
R
D
I
K
E
K
L
C
Y
Honey Bee
Apis mellifera
XP_393368
376
41787
D212
A
E
R
E
I
V
R
D
I
K
E
K
L
C
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786731
376
41813
D212
A
E
R
E
I
V
R
D
I
K
E
K
L
C
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98.8
86.5
N.A.
85.2
85.6
N.A.
63
38.3
38.1
38.3
38.3
38.6
38.6
N.A.
38.1
Protein Similarity:
100
99.3
98.8
91.8
N.A.
91.3
91.1
N.A.
77
57.2
57.2
57
56.5
57
57
N.A.
56
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
73.3
6.6
0
6.6
6.6
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
20
13.3
20
20
20
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
0
0
0
0
0
0
50
0
0
0
0
0
29
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
0
% C
% Asp:
0
0
0
8
0
0
50
50
0
0
0
50
0
0
0
% D
% Glu:
0
50
0
50
0
0
0
0
0
0
50
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
43
0
0
0
0
0
50
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
50
0
0
50
0
0
0
50
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
50
0
50
0
0
0
% K
% Leu:
0
0
0
0
0
50
0
0
0
0
0
0
86
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
50
0
50
0
50
0
0
0
0
0
0
0
0
% R
% Ser:
43
0
0
0
0
0
0
0
0
0
50
0
0
0
0
% S
% Thr:
0
0
50
0
0
0
0
0
0
0
0
0
0
50
8
% T
% Val:
0
0
0
0
0
50
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
0
0
0
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _