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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRAK3
All Species:
27.27
Human Site:
S445
Identified Species:
75
UniProt:
Q9Y616
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y616
NP_009130.2
596
67753
S445
E
V
L
N
T
L
E
S
T
Q
A
S
L
Y
F
Chimpanzee
Pan troglodytes
XP_522458
596
67831
S445
E
V
L
N
T
L
E
S
T
Q
A
S
L
Y
F
Rhesus Macaque
Macaca mulatta
XP_001117080
596
67563
S445
E
V
L
N
T
L
E
S
T
Q
A
S
L
Y
F
Dog
Lupus familis
XP_538271
613
69501
S451
E
V
L
T
T
L
E
S
T
Q
A
S
L
Y
F
Cat
Felis silvestris
Mouse
Mus musculus
NP_082955
609
68437
S458
E
V
L
S
S
L
E
S
T
Q
P
S
L
Y
F
Rat
Rattus norvegicus
NP_001101571
610
68959
S459
E
V
L
N
T
L
E
S
T
Q
P
S
L
Y
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510859
619
68744
T444
E
V
L
E
T
L
E
T
T
R
P
A
L
Y
F
Chicken
Gallus gallus
NP_001025776
691
76730
T537
Y
I
C
G
G
G
S
T
S
G
F
S
M
N
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002661426
657
74009
P479
M
V
L
Q
R
L
I
P
L
H
P
L
P
A
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.3
75.6
N.A.
74.7
75.5
N.A.
56.3
24
N.A.
35.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
98.1
83.5
N.A.
84.2
84.9
N.A.
70.2
42.5
N.A.
51.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
80
93.3
N.A.
66.6
6.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
86.6
33.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
45
12
0
12
0
% A
% Cys:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
78
0
0
12
0
0
78
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
89
% F
% Gly:
0
0
0
12
12
12
0
0
0
12
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% H
% Ile:
0
12
0
0
0
0
12
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
89
0
0
89
0
0
12
0
0
12
78
0
0
% L
% Met:
12
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% M
% Asn:
0
0
0
45
0
0
0
0
0
0
0
0
0
12
0
% N
% Pro:
0
0
0
0
0
0
0
12
0
0
45
0
12
0
0
% P
% Gln:
0
0
0
12
0
0
0
0
0
67
0
0
0
0
0
% Q
% Arg:
0
0
0
0
12
0
0
0
0
12
0
0
0
0
0
% R
% Ser:
0
0
0
12
12
0
12
67
12
0
0
78
0
0
0
% S
% Thr:
0
0
0
12
67
0
0
23
78
0
0
0
0
0
12
% T
% Val:
0
89
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
0
0
0
0
0
0
0
0
0
0
0
0
78
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _