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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSAT1 All Species: 40.61
Human Site: S275 Identified Species: 63.81
UniProt: Q9Y617 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y617 NP_066977.1 370 40423 S275 E K L S S I K S Q T I Y E I I
Chimpanzee Pan troglodytes XP_001149878 370 40347 A275 S S L P S L S A S S I Y E I I
Rhesus Macaque Macaca mulatta XP_001101670 370 40393 S275 E K L S S I K S Q M I Y E I I
Dog Lupus familis XP_533520 370 40417 S275 E K L S S I K S Q M I Y D I I
Cat Felis silvestris
Mouse Mus musculus Q99K85 370 40454 S275 E K L S S I K S Q M I Y E I I
Rat Rattus norvegicus NP_942033 370 40608 S275 E K L S S V K S Q M I Y E I I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514904 235 25578 F170 V C D M S S N F L S Q P V D I
Chicken Gallus gallus XP_424846 354 39008 S259 D K L S L I K S R M I Y D I I
Frog Xenopus laevis NP_001088009 369 40229 S275 E K L S I I K S N M I Y N I I
Zebra Danio Brachydanio rerio NP_956113 368 40505 S274 E R L N K Q K S A L V Y D I I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VAN0 364 39522 S269 A K L A A A K S K L I Y D T I
Honey Bee Apis mellifera XP_396126 371 41433 S277 E K L A I A K S Q K I Y D V I
Nematode Worm Caenorhab. elegans P91856 370 40983 S274 Y E L N L Q K S G M I Y D I I
Sea Urchin Strong. purpuratus XP_001179183 413 45473 S269 E E W S I A K S N L I F D M I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q96255 430 47341 A340 E K K N Q R K A D L L Y N A I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.3 98.1 94.5 N.A. 92.4 91.8 N.A. 53.5 77.5 78.9 74.5 N.A. 61.6 57.1 52.7 53.7
Protein Similarity: 100 96.2 98.6 97.5 N.A. 97.8 97.5 N.A. 59.1 87.8 88.6 87 N.A. 75.9 75.1 71 68.5
P-Site Identity: 100 46.6 93.3 86.6 N.A. 93.3 86.6 N.A. 13.3 66.6 73.3 46.6 N.A. 46.6 60 46.6 40
P-Site Similarity: 100 66.6 93.3 93.3 N.A. 93.3 93.3 N.A. 20 86.6 73.3 73.3 N.A. 73.3 80 66.6 66.6
Percent
Protein Identity: N.A. N.A. N.A. 45.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 58.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 14 7 20 0 14 7 0 0 0 0 7 0 % A
% Cys: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 7 0 0 0 0 0 7 0 0 0 47 7 0 % D
% Glu: 67 14 0 0 0 0 0 0 0 0 0 0 34 0 0 % E
% Phe: 0 0 0 0 0 0 0 7 0 0 0 7 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 20 40 0 0 0 0 80 0 0 67 100 % I
% Lys: 0 67 7 0 7 0 87 0 7 7 0 0 0 0 0 % K
% Leu: 0 0 80 0 14 7 0 0 7 27 7 0 0 0 0 % L
% Met: 0 0 0 7 0 0 0 0 0 47 0 0 0 7 0 % M
% Asn: 0 0 0 20 0 0 7 0 14 0 0 0 14 0 0 % N
% Pro: 0 0 0 7 0 0 0 0 0 0 0 7 0 0 0 % P
% Gln: 0 0 0 0 7 14 0 0 40 0 7 0 0 0 0 % Q
% Arg: 0 7 0 0 0 7 0 0 7 0 0 0 0 0 0 % R
% Ser: 7 7 0 54 47 7 7 80 7 14 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 7 0 0 0 7 0 % T
% Val: 7 0 0 0 0 7 0 0 0 0 7 0 7 7 0 % V
% Trp: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 0 0 0 0 0 0 87 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _