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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPC6
All Species:
6.06
Human Site:
T374
Identified Species:
13.33
UniProt:
Q9Y625
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y625
NP_005699.1
555
62736
T374
Y
N
P
E
E
R
P
T
T
A
A
G
T
S
L
Chimpanzee
Pan troglodytes
A5A6P7
580
65546
S397
E
L
I
Q
K
L
K
S
F
I
S
F
Y
S
A
Rhesus Macaque
Macaca mulatta
XP_001083995
502
56712
G325
E
R
P
T
T
A
A
G
T
S
L
D
R
L
V
Dog
Lupus familis
XP_534162
484
54973
G307
E
R
P
T
T
A
A
G
T
S
L
D
R
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9R087
555
63038
T374
Y
N
P
E
E
R
P
T
T
A
A
G
T
S
L
Rat
Rattus norvegicus
P35053
558
61716
Q367
R
R
A
K
L
A
L
Q
E
K
S
S
T
G
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512088
782
87753
L601
A
G
T
S
L
D
R
L
R
T
I
W
R
T
M
Chicken
Gallus gallus
P50593
550
61065
E364
R
R
G
K
V
T
L
E
A
K
S
S
A
V
A
Frog
Xenopus laevis
NP_001084188
556
63021
R372
K
A
Y
G
P
E
E
R
P
T
T
A
A
G
T
Zebra Danio
Brachydanio rerio
NP_001103189
562
63478
D382
T
A
A
G
T
S
L
D
R
L
R
I
V
W
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24114
626
69013
L442
D
P
D
P
G
M
V
L
F
L
S
T
I
D
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27
83.2
82.5
N.A.
96.7
46.7
N.A.
65.2
49
64.9
67.4
N.A.
22.5
N.A.
N.A.
N.A.
Protein Similarity:
100
45.6
85.9
84.6
N.A.
98
65.7
N.A.
67.9
68.4
77.6
80.2
N.A.
38.8
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
13.3
13.3
N.A.
100
6.6
N.A.
0
0
0
0
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
26.6
26.6
N.A.
100
20
N.A.
13.3
13.3
0
0
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
19
19
0
0
28
19
0
10
19
19
10
19
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
0
10
0
10
0
0
0
19
0
10
0
% D
% Glu:
28
0
0
19
19
10
10
10
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
19
0
0
10
0
0
0
% F
% Gly:
0
10
10
19
10
0
0
19
0
0
0
19
0
19
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
10
10
10
10
0
0
% I
% Lys:
10
0
0
19
10
0
10
0
0
19
0
0
0
0
10
% K
% Leu:
0
10
0
0
19
10
28
19
0
19
19
0
0
19
19
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
37
10
10
0
19
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
19
37
0
0
0
19
10
10
19
0
10
0
28
0
10
% R
% Ser:
0
0
0
10
0
10
0
10
0
19
37
19
0
28
0
% S
% Thr:
10
0
10
19
28
10
0
19
37
19
10
10
28
10
19
% T
% Val:
0
0
0
0
10
0
10
0
0
0
0
0
10
10
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% W
% Tyr:
19
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _