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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SOX21 All Species: 17.27
Human Site: S187 Identified Species: 38
UniProt: Q9Y651 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y651 NP_009015.1 276 28580 S187 A E I S S S S S G L P Y A S S
Chimpanzee Pan troglodytes XP_516895 690 75569 S543 M N G W S N G S Y S M M Q D Q
Rhesus Macaque Macaca mulatta XP_001084162 254 26631 S165 A E I S S S S S G L P Y A S S
Dog Lupus familis XP_542802 578 62829 T496 K M G E V P H T L A T G A L P
Cat Felis silvestris
Mouse Mus musculus Q811W0 276 28591 S187 A E I S S S S S G L P Y A S S
Rat Rattus norvegicus NP_001100320 240 26497 T158 K M G E V P H T L A T S A L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512271 167 19238 F88 L K K D K F A F P V P Y G L G
Chicken Gallus gallus Q9W7R5 280 28778 S187 A E I S S S S S A G S A L P Y
Frog Xenopus laevis B0ZTE1 262 28100 S181 A E M T H S S S S I P Y T S S
Zebra Danio Brachydanio rerio Q6RVD7 245 26782 F166 T E L S P P S F S Y A S P L G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999638 270 29704 P173 I R D F P H H P A L Y P P P H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 23.1 92 22.1 N.A. 99.6 58.3 N.A. 42.3 92.1 77.9 75 N.A. N.A. N.A. N.A. 46
Protein Similarity: 100 28.8 92 30.6 N.A. 99.6 70.2 N.A. 49.6 93.5 84.4 79.3 N.A. N.A. N.A. N.A. 59.4
P-Site Identity: 100 13.3 100 6.6 N.A. 100 6.6 N.A. 13.3 53.3 60 20 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 20 100 13.3 N.A. 100 13.3 N.A. 33.3 53.3 80 26.6 N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 46 0 0 0 0 0 10 0 19 19 10 10 46 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 10 0 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 55 0 19 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 10 0 10 0 19 0 0 0 0 0 0 0 % F
% Gly: 0 0 28 0 0 0 10 0 28 10 0 10 10 0 19 % G
% His: 0 0 0 0 10 10 28 0 0 0 0 0 0 0 10 % H
% Ile: 10 0 37 0 0 0 0 0 0 10 0 0 0 0 0 % I
% Lys: 19 10 10 0 10 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 10 0 0 0 0 0 19 37 0 0 10 37 0 % L
% Met: 10 19 10 0 0 0 0 0 0 0 10 10 0 0 0 % M
% Asn: 0 10 0 0 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 19 28 0 10 10 0 46 10 19 19 19 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % Q
% Arg: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 46 46 46 55 55 19 10 10 19 0 37 37 % S
% Thr: 10 0 0 10 0 0 0 19 0 0 19 0 10 0 0 % T
% Val: 0 0 0 0 19 0 0 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 10 10 46 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _