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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COPG All Species: 53.64
Human Site: S163 Identified Species: 78.67
UniProt: Q9Y678 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y678 NP_057212.1 874 97718 S163 S S S A L V S S L H L L K C S
Chimpanzee Pan troglodytes XP_001141317 874 97700 S163 S S S A L V S S L H L L K C S
Rhesus Macaque Macaca mulatta XP_001095932 720 80896 L48 P R R C L H I L T K I L Y L L
Dog Lupus familis XP_533723 874 97733 S163 S S S A L V S S L H L L K C S
Cat Felis silvestris
Mouse Mus musculus Q9QZE5 874 97494 S163 S S S A L V S S L H L L K C S
Rat Rattus norvegicus Q4AEF8 874 97595 S163 S S S A L V S S L H L L K C S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511377 871 97400 S163 S S S A L V S S L H M M K I S
Chicken Gallus gallus NP_001025768 874 97583 S163 S S S A L V S S L H L L K T S
Frog Xenopus laevis Q6DKD7 872 97774 S163 S S S A L V S S L N M T K I S
Zebra Danio Brachydanio rerio Q9PUE4 873 97510 S163 S S S A L V S S L H M V K M S
Tiger Blowfish Takifugu rubipres Q9I8E6 873 97451 S163 S S S A L V S S L H M V K M S
Fruit Fly Dros. melanogaster NP_524608 879 97258 S164 S C A A L V S S L R L A N T A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22498 870 96284 S159 S S S A I V S S I H L M R K S
Sea Urchin Strong. purpuratus XP_784737 871 96880 S161 S S A A L C S S L H L L K Q S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q0WW26 886 98472 G165 S S A A L V S G L H L L K T N
Baker's Yeast Sacchar. cerevisiae P32074 935 104813 S160 S S A A L C T S Y H L L P I S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 67.8 98.6 N.A. 97.2 97.1 N.A. 81.6 93.3 79.8 81.8 81.4 60.1 N.A. 56.2 70.4
Protein Similarity: 100 99.8 76 99.1 N.A. 98.5 98.4 N.A. 91.7 96.1 90.1 92.2 91.8 74.5 N.A. 75.6 84.2
P-Site Identity: 100 100 13.3 100 N.A. 100 100 N.A. 80 93.3 73.3 80 80 53.3 N.A. 66.6 80
P-Site Similarity: 100 100 20 100 N.A. 100 100 N.A. 93.3 93.3 86.6 93.3 93.3 66.6 N.A. 93.3 86.6
Percent
Protein Identity: N.A. N.A. N.A. 51.1 34.3 N.A.
Protein Similarity: N.A. N.A. N.A. 69.8 55.1 N.A.
P-Site Identity: N.A. N.A. N.A. 73.3 60 N.A.
P-Site Similarity: N.A. N.A. N.A. 86.6 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 25 94 0 0 0 0 0 0 0 7 0 0 7 % A
% Cys: 0 7 0 7 0 13 0 0 0 0 0 0 0 32 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 7 0 0 0 82 0 0 0 0 0 % H
% Ile: 0 0 0 0 7 0 7 0 7 0 7 0 0 19 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 7 0 0 75 7 0 % K
% Leu: 0 0 0 0 94 0 0 7 82 0 69 63 0 7 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 25 13 0 13 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 7 0 0 7 0 7 % N
% Pro: 7 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % Q
% Arg: 0 7 7 0 0 0 0 0 0 7 0 0 7 0 0 % R
% Ser: 94 88 69 0 0 0 88 88 0 0 0 0 0 0 82 % S
% Thr: 0 0 0 0 0 0 7 0 7 0 0 7 0 19 0 % T
% Val: 0 0 0 0 0 82 0 0 0 0 0 13 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 7 0 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _