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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AUP1 All Species: 1.21
Human Site: S354 Identified Species: 2.42
UniProt: Q9Y679 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y679 NP_853553.1 476 53028 S354 A Q S S F P P S P G P S P D V
Chimpanzee Pan troglodytes XP_001161094 410 45740 A298 P S P D V Q L A T L A Q R V K
Rhesus Macaque Macaca mulatta XP_001110957 410 45712 A298 T S P D V Q L A T L A Q R V K
Dog Lupus familis XP_852590 410 45740 A298 P S P D V Q L A A L A Q R V K
Cat Felis silvestris
Mouse Mus musculus P70295 410 46103 T298 P S S D V Q L T T L A H R V K
Rat Rattus norvegicus A1L134 410 46181 T298 P S S D V Q L T I L A Q R V K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001232437 481 51725 G351 P S S L S G I G S F A P E D T
Frog Xenopus laevis B1H1N7 399 44798 I286 Q P L S P T H I Q M A Q H V K
Zebra Danio Brachydanio rerio Q6PBN5 423 47395 Q311 R I A R L A Q Q V K E V L P D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392941 392 44951 N280 Q S R R F D R N S P N S Q V I
Nematode Worm Caenorhab. elegans P34426 390 44209 K278 S D A T E A A K R L R T D R E
Sea Urchin Strong. purpuratus XP_786775 442 49109 H328 I P R H I I K H D L E T T N S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.9 85 81.7 N.A. 77.7 78.7 N.A. N.A. 42 43.7 47.9 N.A. N.A. 26.2 30.8 22.9
Protein Similarity: 100 85.9 85.2 83.4 N.A. 80 80.8 N.A. N.A. 55 55.6 62.8 N.A. N.A. 44.9 47.2 39
P-Site Identity: 100 0 0 0 N.A. 6.6 6.6 N.A. N.A. 13.3 6.6 0 N.A. N.A. 13.3 0 0
P-Site Similarity: 100 6.6 6.6 6.6 N.A. 13.3 13.3 N.A. N.A. 13.3 6.6 6.6 N.A. N.A. 26.6 26.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 17 0 0 17 9 25 9 0 59 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 42 0 9 0 0 9 0 0 0 9 17 9 % D
% Glu: 0 0 0 0 9 0 0 0 0 0 17 0 9 0 9 % E
% Phe: 0 0 0 0 17 0 0 0 0 9 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 9 0 9 0 9 0 0 0 0 0 % G
% His: 0 0 0 9 0 0 9 9 0 0 0 9 9 0 0 % H
% Ile: 9 9 0 0 9 9 9 9 9 0 0 0 0 0 9 % I
% Lys: 0 0 0 0 0 0 9 9 0 9 0 0 0 0 50 % K
% Leu: 0 0 9 9 9 0 42 0 0 59 0 0 9 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 9 0 0 9 0 0 9 0 % N
% Pro: 42 17 25 0 9 9 9 0 9 9 9 9 9 9 0 % P
% Gln: 17 9 0 0 0 42 9 9 9 0 0 42 9 0 0 % Q
% Arg: 9 0 17 17 0 0 9 0 9 0 9 0 42 9 0 % R
% Ser: 9 59 34 17 9 0 0 9 17 0 0 17 0 0 9 % S
% Thr: 9 0 0 9 0 9 0 17 25 0 0 17 9 0 9 % T
% Val: 0 0 0 0 42 0 0 0 9 0 0 9 0 59 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _