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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GMEB1 All Species: 24.85
Human Site: S454 Identified Species: 54.67
UniProt: Q9Y692 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y692 NP_006573.2 573 62591 S454 R Y A T V V S S A K S S S P D
Chimpanzee Pan troglodytes XP_524637 573 62602 S454 R Y A T V V S S A K S S S P D
Rhesus Macaque Macaca mulatta XP_001115680 239 25769 A138 I H P S S S L A L L S S T A M
Dog Lupus familis XP_544456 573 62612 S454 R Y A T V V S S A K S S S P D
Cat Felis silvestris
Mouse Mus musculus Q9JL60 562 61054 S443 R Y A T V V S S A K S N S P D
Rat Rattus norvegicus Q9QUZ8 562 61176 S443 R Y A T V V S S A K S N S P D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511013 533 57177 Y431 A S P L L G G Y T V L A S S G
Chicken Gallus gallus XP_001232353 573 62034 S452 R Y A T V V S S S K T N S S D
Frog Xenopus laevis NP_001085124 502 54279 Q398 T L A S I G Q Q F S L G G V R
Zebra Danio Brachydanio rerio XP_697359 501 53885 S400 Q T Q S P L I S G Y T L L T S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_497762 376 42751 I275 P M S F W S Q I K R S G F I S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 41.5 98.9 N.A. 93.1 93.7 N.A. 38.5 87 58.1 36.1 N.A. N.A. N.A. 20.9 N.A.
Protein Similarity: 100 99.8 41.5 99.3 N.A. 95.9 95.8 N.A. 56.2 93.5 73.8 57.2 N.A. N.A. N.A. 36.4 N.A.
P-Site Identity: 100 100 13.3 100 N.A. 93.3 93.3 N.A. 6.6 73.3 6.6 6.6 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 100 40 100 N.A. 100 100 N.A. 20 93.3 20 33.3 N.A. N.A. N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 64 0 0 0 0 10 46 0 0 10 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 55 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 10 0 0 0 0 10 0 0 0 10 0 0 % F
% Gly: 0 0 0 0 0 19 10 0 10 0 0 19 10 0 10 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 10 0 10 10 0 0 0 0 0 10 0 % I
% Lys: 0 0 0 0 0 0 0 0 10 55 0 0 0 0 0 % K
% Leu: 0 10 0 10 10 10 10 0 10 10 19 10 10 0 0 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 28 0 0 0 % N
% Pro: 10 0 19 0 10 0 0 0 0 0 0 0 0 46 0 % P
% Gln: 10 0 10 0 0 0 19 10 0 0 0 0 0 0 0 % Q
% Arg: 55 0 0 0 0 0 0 0 0 10 0 0 0 0 10 % R
% Ser: 0 10 10 28 10 19 55 64 10 10 64 37 64 19 19 % S
% Thr: 10 10 0 55 0 0 0 0 10 0 19 0 10 10 0 % T
% Val: 0 0 0 0 55 55 0 0 0 10 0 0 0 10 0 % V
% Trp: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 55 0 0 0 0 0 10 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _