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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LHFP All Species: 22.42
Human Site: S51 Identified Species: 49.33
UniProt: Q9Y693 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y693 NP_005771.1 200 21598 S51 F G T F R R C S Y P V H D E S
Chimpanzee Pan troglodytes XP_529109 211 23015 F70 K P V S F S T F R R C N Y P V
Rhesus Macaque Macaca mulatta XP_001101350 220 23740 N51 F S T F R R C N Y P V R G E G
Dog Lupus familis XP_543123 264 28804 S51 F G T F R R C S Y P V H D E S
Cat Felis silvestris
Mouse Mus musculus Q8BM86 200 21608 S51 F G T F R R C S Y P V H D E S
Rat Rattus norvegicus Q5BJS2 200 21648 S51 F G T F R R C S Y P V H D E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512067 200 21510 S51 F G T F R R C S Y P V H D E S
Chicken Gallus gallus Q7ZZL8 221 24401 G63 T P Q A G Y F G L F S Y C I G
Frog Xenopus laevis Q66IV3 218 23764 G60 T P Q A G Y F G L F H F C I G
Zebra Danio Brachydanio rerio Q5PRC1 200 21349 S51 F G T F R R C S Y P I R D E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001199390 263 28182 V114 T L P V H F G V F R R C N Y P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51.6 57.7 65.5 N.A. 97 97 N.A. 94 22.1 22.9 86 N.A. N.A. N.A. N.A. 31.5
Protein Similarity: 100 65.4 70.4 67.8 N.A. 98 97.5 N.A. 95.5 38.4 44 94 N.A. N.A. N.A. N.A. 45.6
P-Site Identity: 100 0 66.6 100 N.A. 100 100 N.A. 100 0 0 80 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 6.6 73.3 100 N.A. 100 100 N.A. 100 6.6 0 93.3 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 19 0 0 0 0 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 64 0 0 0 10 10 19 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 55 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 64 0 % E
% Phe: 64 0 0 64 10 10 19 10 10 19 0 10 0 0 0 % F
% Gly: 0 55 0 0 19 0 10 19 0 0 0 0 10 0 28 % G
% His: 0 0 0 0 10 0 0 0 0 0 10 46 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 10 0 0 19 0 % I
% Lys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 0 0 0 0 0 0 19 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 0 0 0 10 10 0 0 % N
% Pro: 0 28 10 0 0 0 0 0 0 64 0 0 0 10 10 % P
% Gln: 0 0 19 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 64 64 0 0 10 19 10 19 0 0 0 % R
% Ser: 0 10 0 10 0 10 0 55 0 0 10 0 0 0 46 % S
% Thr: 28 0 64 0 0 0 10 0 0 0 0 0 0 0 0 % T
% Val: 0 0 10 10 0 0 0 10 0 0 55 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 19 0 0 64 0 0 10 10 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _