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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LHFP All Species: 26.67
Human Site: T46 Identified Species: 58.67
UniProt: Q9Y693 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y693 NP_005771.1 200 21598 T46 G K P V S F G T F R R C S Y P
Chimpanzee Pan troglodytes XP_529109 211 23015 V65 G S Q M G K P V S F S T F R R
Rhesus Macaque Macaca mulatta XP_001101350 220 23740 T46 G K P V S F S T F R R C N Y P
Dog Lupus familis XP_543123 264 28804 T46 G K S V S F G T F R R C S Y P
Cat Felis silvestris
Mouse Mus musculus Q8BM86 200 21608 T46 G K P V S F G T F R R C S Y P
Rat Rattus norvegicus Q5BJS2 200 21648 T46 G K P V S F G T F R R C S Y P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512067 200 21510 T46 G K P V S F G T F R R C S Y P
Chicken Gallus gallus Q7ZZL8 221 24401 Q58 G D S I D T P Q A G Y F G L F
Frog Xenopus laevis Q66IV3 218 23764 Q55 G D G V D T P Q A G Y F G L F
Zebra Danio Brachydanio rerio Q5PRC1 200 21349 T46 G K P V S F G T F R R C S Y P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001199390 263 28182 P109 H M F N G T L P V H F G V F R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51.6 57.7 65.5 N.A. 97 97 N.A. 94 22.1 22.9 86 N.A. N.A. N.A. N.A. 31.5
Protein Similarity: 100 65.4 70.4 67.8 N.A. 98 97.5 N.A. 95.5 38.4 44 94 N.A. N.A. N.A. N.A. 45.6
P-Site Identity: 100 6.6 86.6 93.3 N.A. 100 100 N.A. 100 6.6 13.3 100 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 13.3 93.3 93.3 N.A. 100 100 N.A. 100 13.3 13.3 100 N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 19 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 64 0 0 0 % C
% Asp: 0 19 0 0 19 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 10 0 0 64 0 0 64 10 10 19 10 10 19 % F
% Gly: 91 0 10 0 19 0 55 0 0 19 0 10 19 0 0 % G
% His: 10 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 64 0 0 0 10 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 10 0 0 0 0 0 0 19 0 % L
% Met: 0 10 0 10 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 0 0 55 0 0 0 28 10 0 0 0 0 0 0 64 % P
% Gln: 0 0 10 0 0 0 0 19 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 64 64 0 0 10 19 % R
% Ser: 0 10 19 0 64 0 10 0 10 0 10 0 55 0 0 % S
% Thr: 0 0 0 0 0 28 0 64 0 0 0 10 0 0 0 % T
% Val: 0 0 0 73 0 0 0 10 10 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 19 0 0 64 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _