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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC22A7
All Species:
24.55
Human Site:
S166
Identified Species:
49.09
UniProt:
Q9Y694
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y694
NP_006663.2
548
60026
S166
A
V
A
F
G
Y
L
S
D
R
F
G
R
R
R
Chimpanzee
Pan troglodytes
XP_001137440
548
60007
S166
A
V
A
F
G
Y
L
S
D
R
F
G
R
R
R
Rhesus Macaque
Macaca mulatta
XP_001115870
550
60174
A156
A
M
V
F
G
Y
L
A
D
R
L
G
R
R
K
Dog
Lupus familis
XP_854865
524
57401
C130
V
M
E
W
D
L
V
C
E
A
R
P
L
R
D
Cat
Felis silvestris
Mouse
Mus musculus
Q91WU2
540
59595
S164
A
V
V
Y
G
Y
L
S
D
R
F
G
R
R
R
Rat
Rattus norvegicus
Q5RLM2
535
58635
W132
S
S
T
I
A
T
E
W
D
L
V
C
Q
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513142
551
59935
T162
G
L
N
Q
I
T
V
T
S
F
F
V
G
V
L
Chicken
Gallus gallus
XP_415009
542
60370
S159
A
V
V
F
G
Y
L
S
D
R
F
G
R
K
S
Frog
Xenopus laevis
Q66J52
552
61646
S158
S
I
L
F
G
G
L
S
D
K
F
G
R
R
P
Zebra Danio
Brachydanio rerio
Q6NYN7
560
61953
S164
A
I
V
F
G
G
L
S
D
R
F
G
R
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCA2
548
60985
S152
S
L
I
F
G
Q
M
S
D
K
L
G
R
K
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U539
585
65444
A176
N
C
L
F
G
Y
V
A
D
K
F
G
R
R
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
38.3
39.9
N.A.
76.2
78
N.A.
68.5
52.3
38.5
39.4
N.A.
34.4
N.A.
28.8
N.A.
Protein Similarity:
100
99.8
57.2
54
N.A.
84.6
87.5
N.A.
78.2
70
57.7
56.6
N.A.
54.2
N.A.
47.5
N.A.
P-Site Identity:
100
100
66.6
6.6
N.A.
86.6
13.3
N.A.
6.6
80
60
73.3
N.A.
40
N.A.
60
N.A.
P-Site Similarity:
100
100
86.6
33.3
N.A.
93.3
33.3
N.A.
26.6
86.6
80
80
N.A.
73.3
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
17
0
9
0
0
17
0
9
0
0
0
0
0
% A
% Cys:
0
9
0
0
0
0
0
9
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
9
0
0
0
84
0
0
0
0
0
9
% D
% Glu:
0
0
9
0
0
0
9
0
9
0
0
0
0
0
0
% E
% Phe:
0
0
0
67
0
0
0
0
0
9
67
0
0
0
0
% F
% Gly:
9
0
0
0
75
17
0
0
0
0
0
75
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
17
9
9
9
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
25
0
0
0
17
9
% K
% Leu:
0
17
17
0
0
9
59
0
0
9
17
0
9
0
9
% L
% Met:
0
17
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
17
% P
% Gln:
0
0
0
9
0
9
0
0
0
0
0
0
9
9
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
50
9
0
75
67
42
% R
% Ser:
25
9
0
0
0
0
0
59
9
0
0
0
0
0
9
% S
% Thr:
0
0
9
0
0
17
0
9
0
0
0
0
0
0
0
% T
% Val:
9
34
34
0
0
0
25
0
0
0
9
9
0
9
9
% V
% Trp:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
50
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _