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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLIC4
All Species:
31.82
Human Site:
S226
Identified Species:
87.5
UniProt:
Q9Y696
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y696
NP_039234.1
253
28772
S226
R
Y
L
T
N
A
Y
S
R
D
E
F
T
N
T
Chimpanzee
Pan troglodytes
XP_001168510
253
28927
S226
R
Y
L
T
N
A
Y
S
R
D
E
F
T
N
T
Rhesus Macaque
Macaca mulatta
XP_001106485
253
28740
S226
R
Y
L
T
N
A
Y
S
R
D
E
F
T
N
T
Dog
Lupus familis
XP_544493
253
28695
S226
R
Y
L
T
N
A
Y
S
R
D
E
F
T
N
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYB1
253
28711
S226
R
Y
L
T
N
A
Y
S
R
D
E
F
T
N
T
Rat
Rattus norvegicus
Q9Z0W7
253
28614
S226
R
Y
L
T
N
A
Y
S
R
D
E
F
T
N
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417741
312
35519
S285
R
Y
L
S
N
A
Y
S
R
D
E
F
T
N
T
Frog
Xenopus laevis
NP_001089196
252
28572
S225
R
Y
L
S
N
A
Y
S
K
D
E
F
T
N
T
Zebra Danio
Brachydanio rerio
NP_958894
252
28352
K225
R
Y
L
N
N
A
Y
K
R
E
E
F
T
N
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.2
99.5
98.4
N.A.
98.8
97.6
N.A.
N.A.
73
85.7
85.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
94.8
100
99.5
N.A.
99.5
98.4
N.A.
N.A.
76.9
93.6
93.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
86.6
80
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
89
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
12
100
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
12
12
0
0
0
0
0
0
% K
% Leu:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
100
0
0
0
0
0
0
0
0
100
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
100
0
0
0
0
0
0
0
89
0
0
0
0
0
0
% R
% Ser:
0
0
0
23
0
0
0
89
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
67
0
0
0
0
0
0
0
0
100
0
100
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
100
0
0
0
0
100
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _