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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP46A1
All Species:
8.48
Human Site:
S28
Identified Species:
15.56
UniProt:
Q9Y6A2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6A2
NP_006659.1
500
56821
S28
T
F
V
H
R
A
R
S
R
Y
E
H
I
P
G
Chimpanzee
Pan troglodytes
XP_510158
696
78477
T65
S
F
H
S
P
Q
G
T
W
W
L
R
S
T
P
Rhesus Macaque
Macaca mulatta
XP_001103622
505
57211
A28
T
F
L
R
R
A
E
A
K
S
P
A
Q
G
H
Dog
Lupus familis
XP_537552
477
54557
K29
G
H
L
P
Y
F
W
K
K
D
E
V
C
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVK8
500
56796
S28
T
F
V
H
R
A
R
S
R
Y
E
H
I
P
G
Rat
Rattus norvegicus
P51538
503
57793
L36
S
H
G
I
F
K
K
L
G
I
P
G
P
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512720
452
51454
L39
P
E
A
V
K
E
F
L
M
S
P
Q
Y
Q
K
Chicken
Gallus gallus
XP_421360
499
57589
A31
C
Y
V
R
R
V
H
A
A
Y
D
H
I
P
G
Frog
Xenopus laevis
NP_001104219
504
58010
M34
G
Y
I
Q
Y
I
H
M
K
Y
D
H
I
P
G
Zebra Danio
Brachydanio rerio
NP_001018358
501
57814
Q33
L
Y
I
H
H
L
H
Q
K
Y
D
H
I
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27589
501
57896
P32
R
R
G
N
G
I
L
P
G
P
R
P
L
P
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780966
507
57852
Y35
A
A
I
L
R
K
E
Y
E
L
K
D
V
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O23365
580
65156
S44
Q
T
I
S
S
V
N
S
R
R
A
S
V
S
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.4
96.4
87.5
N.A.
94.8
26.4
N.A.
52.5
57.7
51.5
47.3
N.A.
31.3
N.A.
N.A.
40.2
Protein Similarity:
100
71.1
97.4
91.1
N.A.
98.1
47.1
N.A.
68.1
75.4
70
66.4
N.A.
52.5
N.A.
N.A.
59.9
P-Site Identity:
100
6.6
26.6
6.6
N.A.
100
0
N.A.
0
46.6
33.3
40
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
26.6
46.6
20
N.A.
100
13.3
N.A.
6.6
66.6
60
66.6
N.A.
20
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
0
24
0
16
8
0
8
8
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
24
8
0
0
0
% D
% Glu:
0
8
0
0
0
8
16
0
8
0
24
0
0
0
0
% E
% Phe:
0
31
0
0
8
8
8
0
0
0
0
0
0
0
8
% F
% Gly:
16
0
16
0
8
0
8
0
16
0
0
8
0
16
39
% G
% His:
0
16
8
24
8
0
24
0
0
0
0
39
0
0
8
% H
% Ile:
0
0
31
8
0
16
0
0
0
8
0
0
39
0
8
% I
% Lys:
0
0
0
0
8
16
8
8
31
0
8
0
0
8
8
% K
% Leu:
8
0
16
8
0
8
8
16
0
8
8
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
8
8
0
0
8
0
8
24
8
8
54
16
% P
% Gln:
8
0
0
8
0
8
0
8
0
0
0
8
8
8
0
% Q
% Arg:
8
8
0
16
39
0
16
0
24
8
8
8
0
0
8
% R
% Ser:
16
0
0
16
8
0
0
24
0
16
0
8
8
8
0
% S
% Thr:
24
8
0
0
0
0
0
8
0
0
0
0
0
8
8
% T
% Val:
0
0
24
8
0
16
0
0
0
0
0
8
16
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
8
8
0
0
0
0
0
% W
% Tyr:
0
24
0
0
16
0
0
8
0
39
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _