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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SAR1B All Species: 53.64
Human Site: S143 Identified Species: 78.67
UniProt: Q9Y6B6 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6B6 NP_001028675.1 198 22410 S143 I D R P E A I S E E R L R E M
Chimpanzee Pan troglodytes XP_001167508 176 20070 S121 I D R P E A I S E E R L R E M
Rhesus Macaque Macaca mulatta XP_001109853 198 22377 S143 I D R P E A I S E E R L R E M
Dog Lupus familis XP_538630 198 22404 S143 I D R P E A I S E E R L R E M
Cat Felis silvestris
Mouse Mus musculus Q9CQC9 198 22363 S143 I D R P E A I S E E R L R E M
Rat Rattus norvegicus Q5HZY2 198 22391 S143 I D R P E A I S E E R L R E M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506794 198 22407 S143 I D R P E A I S E E K L R E I
Chicken Gallus gallus NP_001025792 194 22030 S139 I D R P E A I S E E R L R E M
Frog Xenopus laevis NP_001087684 198 22372 S143 I D R P E A I S E E K L R E I
Zebra Danio Brachydanio rerio NP_001019548 198 22210 S143 I D K P E A I S E E K L R E I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_732717 193 21793 S138 I D K P G A A S E D E L R N V
Honey Bee Apis mellifera XP_393115 193 21812 S138 I D K P G A A S E D E L R N Y
Nematode Worm Caenorhab. elegans Q23445 193 21690 S139 I D K P G A L S E D Q L K W Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04834 193 22012 S138 I D I P Y A A S E D E L R Y H
Baker's Yeast Sacchar. cerevisiae P20606 190 21432 A136 I L G N K I D A P N A V S E A
Red Bread Mold Neurospora crassa P0C583 189 21564 E135 G N K I D H P E A V S E D E L
Conservation
Percent
Protein Identity: 100 88.3 99.4 98.9 N.A. 98.9 98.9 N.A. 89.9 95.4 87.8 91.9 N.A. 70.7 71.7 63.6 N.A.
Protein Similarity: 100 88.8 100 100 N.A. 100 100 N.A. 97.4 96.9 95.9 95.9 N.A. 83.3 83.8 81.8 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 86.6 100 86.6 80 N.A. 53.3 53.3 46.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 73.3 66.6 80 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 60.6 59 60.6
Protein Similarity: N.A. N.A. N.A. 76.2 70.2 77.2
P-Site Identity: N.A. N.A. N.A. 53.3 13.3 6.6
P-Site Similarity: N.A. N.A. N.A. 60 33.3 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 88 19 7 7 0 7 0 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 88 0 0 7 0 7 0 0 25 0 0 7 0 0 % D
% Glu: 0 0 0 0 63 0 0 7 88 63 19 7 0 75 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 0 7 0 19 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 7 % H
% Ile: 94 0 7 7 0 7 63 0 0 0 0 0 0 0 19 % I
% Lys: 0 0 32 0 7 0 0 0 0 0 19 0 7 0 0 % K
% Leu: 0 7 0 0 0 0 7 0 0 0 0 88 0 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 44 % M
% Asn: 0 7 0 7 0 0 0 0 0 7 0 0 0 13 0 % N
% Pro: 0 0 0 88 0 0 7 0 7 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 7 % Q
% Arg: 0 0 57 0 0 0 0 0 0 0 44 0 82 0 0 % R
% Ser: 0 0 0 0 0 0 0 88 0 0 7 0 7 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 7 0 7 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % W
% Tyr: 0 0 0 0 7 0 0 0 0 0 0 0 0 7 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _