Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SAR1B All Species: 51.82
Human Site: T158 Identified Species: 76
UniProt: Q9Y6B6 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6B6 NP_001028675.1 198 22410 T158 F G L Y G Q T T G K G S I S L
Chimpanzee Pan troglodytes XP_001167508 176 20070 T136 F G L Y G Q T T G K G S V S L
Rhesus Macaque Macaca mulatta XP_001109853 198 22377 T158 F G L Y G Q T T G K G S V S L
Dog Lupus familis XP_538630 198 22404 T158 F G L Y G Q T T G K G N V S L
Cat Felis silvestris
Mouse Mus musculus Q9CQC9 198 22363 T158 F G L Y G Q T T G K G S V S L
Rat Rattus norvegicus Q5HZY2 198 22391 T158 F G L Y G Q T T G K G S V S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506794 198 22407 T158 F G L Y G Q T T G K G N V P L
Chicken Gallus gallus NP_001025792 194 22030 T154 F G L Y G Q T T G K G N I P L
Frog Xenopus laevis NP_001087684 198 22372 T158 F G L Y G Q T T G K G N V P L
Zebra Danio Brachydanio rerio NP_001019548 198 22210 T158 F G L Y G Q T T G K G N I P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_732717 193 21793 T153 F G L Y Q L T T G K G K V A R
Honey Bee Apis mellifera XP_393115 193 21812 T153 F N L Y G Q T T G K G K I S R
Nematode Worm Caenorhab. elegans Q23445 193 21690 T154 L N I Q H M C T G K G D V S R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04834 193 22012 T153 L G L S N F T T G K G K V N L
Baker's Yeast Sacchar. cerevisiae P20606 190 21432 L151 E L R S A L G L L N T T G S Q
Red Bread Mold Neurospora crassa P0C583 189 21564 Q150 R Q R L G L W Q T T G K G R V
Conservation
Percent
Protein Identity: 100 88.3 99.4 98.9 N.A. 98.9 98.9 N.A. 89.9 95.4 87.8 91.9 N.A. 70.7 71.7 63.6 N.A.
Protein Similarity: 100 88.8 100 100 N.A. 100 100 N.A. 97.4 96.9 95.9 95.9 N.A. 83.3 83.8 81.8 N.A.
P-Site Identity: 100 93.3 93.3 86.6 N.A. 93.3 93.3 N.A. 80 86.6 80 86.6 N.A. 60 80 33.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 93.3 93.3 93.3 N.A. 73.3 80 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 60.6 59 60.6
Protein Similarity: N.A. N.A. N.A. 76.2 70.2 77.2
P-Site Identity: N.A. N.A. N.A. 53.3 6.6 13.3
P-Site Similarity: N.A. N.A. N.A. 66.6 13.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 7 0 0 0 0 0 0 0 0 7 0 % A
% Cys: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % D
% Glu: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 75 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 75 0 0 75 0 7 0 88 0 94 0 13 0 0 % G
% His: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 0 0 0 0 0 0 0 0 0 25 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 88 0 25 0 0 0 % K
% Leu: 13 7 82 7 0 19 0 7 7 0 0 0 0 0 69 % L
% Met: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 13 0 0 7 0 0 0 0 7 0 32 0 7 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 25 0 % P
% Gln: 0 7 0 7 7 69 0 7 0 0 0 0 0 0 7 % Q
% Arg: 7 0 13 0 0 0 0 0 0 0 0 0 0 7 19 % R
% Ser: 0 0 0 13 0 0 0 0 0 0 0 32 0 57 0 % S
% Thr: 0 0 0 0 0 0 82 88 7 7 7 7 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 63 0 7 % V
% Trp: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 75 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _