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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SAR1B All Species: 33.64
Human Site: T65 Identified Species: 49.33
UniProt: Q9Y6B6 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6B6 NP_001028675.1 198 22410 T65 H P T S E E L T I A G M T F T
Chimpanzee Pan troglodytes XP_001167508 176 20070 T56 R L G Q H V P T L H P T R R V
Rhesus Macaque Macaca mulatta XP_001109853 198 22377 T65 H P T S E E L T I A G M T F T
Dog Lupus familis XP_538630 198 22404 T65 H P T S E E L T I A G M T F T
Cat Felis silvestris
Mouse Mus musculus Q9CQC9 198 22363 T65 H P T S E E L T I A G M T F T
Rat Rattus norvegicus Q5HZY2 198 22391 T65 H P T S E E L T I A G M T F T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506794 198 22407 T65 H P T S E E L T I A G M T F T
Chicken Gallus gallus NP_001025792 194 22030 M65 H P T S E E L M T F T T F D L
Frog Xenopus laevis NP_001087684 198 22372 T65 H P T S E E L T I A G M T F T
Zebra Danio Brachydanio rerio NP_001019548 198 22210 T65 H P T S E E L T I A G M T F T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_732717 193 21793 R65 E L S I G N M R F T T F D L G
Honey Bee Apis mellifera XP_393115 193 21812 R65 E L S I G N M R F T T F D L G
Nematode Worm Caenorhab. elegans Q23445 193 21690 G64 S E Q M S L G G I S F T T Y D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04834 193 22012 K65 E L S I G K I K F K A F D L G
Baker's Yeast Sacchar. cerevisiae P20606 190 21432 I64 P T S E E L A I G N I K F T T
Red Bread Mold Neurospora crassa P0C583 189 21564 T67 S V G N V K F T T F D L G G H
Conservation
Percent
Protein Identity: 100 88.3 99.4 98.9 N.A. 98.9 98.9 N.A. 89.9 95.4 87.8 91.9 N.A. 70.7 71.7 63.6 N.A.
Protein Similarity: 100 88.8 100 100 N.A. 100 100 N.A. 97.4 96.9 95.9 95.9 N.A. 83.3 83.8 81.8 N.A.
P-Site Identity: 100 6.6 100 100 N.A. 100 100 N.A. 100 46.6 100 100 N.A. 0 0 13.3 N.A.
P-Site Similarity: 100 13.3 100 100 N.A. 100 100 N.A. 100 46.6 100 100 N.A. 13.3 13.3 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 60.6 59 60.6
Protein Similarity: N.A. N.A. N.A. 76.2 70.2 77.2
P-Site Identity: N.A. N.A. N.A. 0 13.3 6.6
P-Site Similarity: N.A. N.A. N.A. 20 20 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 7 0 0 50 7 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 7 0 19 7 7 % D
% Glu: 19 7 0 7 63 57 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 7 0 19 13 7 19 13 50 0 % F
% Gly: 0 0 13 0 19 0 7 7 7 0 50 0 7 7 19 % G
% His: 57 0 0 0 7 0 0 0 0 7 0 0 0 0 7 % H
% Ile: 0 0 0 19 0 0 7 7 57 0 7 0 0 0 0 % I
% Lys: 0 0 0 0 0 13 0 7 0 7 0 7 0 0 0 % K
% Leu: 0 25 0 0 0 13 57 0 7 0 0 7 0 19 7 % L
% Met: 0 0 0 7 0 0 13 7 0 0 0 50 0 0 0 % M
% Asn: 0 0 0 7 0 13 0 0 0 7 0 0 0 0 0 % N
% Pro: 7 57 0 0 0 0 7 0 0 0 7 0 0 0 0 % P
% Gln: 0 0 7 7 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 7 0 0 0 0 0 0 13 0 0 0 0 7 7 0 % R
% Ser: 13 0 25 57 7 0 0 0 0 7 0 0 0 0 0 % S
% Thr: 0 7 57 0 0 0 0 63 13 13 19 19 57 7 57 % T
% Val: 0 7 0 0 7 7 0 0 0 0 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _