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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SAR1B All Species: 65.45
Human Site: Y186 Identified Species: 96
UniProt: Q9Y6B6 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6B6 NP_001028675.1 198 22410 Y186 S V L K R Q G Y G E G F R W M
Chimpanzee Pan troglodytes XP_001167508 176 20070 Y164 S V L K R Q G Y G E G F R W M
Rhesus Macaque Macaca mulatta XP_001109853 198 22377 Y186 S V L K R Q G Y G E G F R W M
Dog Lupus familis XP_538630 198 22404 Y186 S V L K R Q G Y G E G F R W M
Cat Felis silvestris
Mouse Mus musculus Q9CQC9 198 22363 Y186 S V L K R Q G Y G E G F R W M
Rat Rattus norvegicus Q5HZY2 198 22391 Y186 S V L K R Q G Y G E G F R W M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506794 198 22407 Y186 S V L K R Q G Y G E G F R W L
Chicken Gallus gallus NP_001025792 194 22030 Y182 S V L K R Q G Y G E G F R W M
Frog Xenopus laevis NP_001087684 198 22372 Y186 S V L K R Q G Y G E G F R W L
Zebra Danio Brachydanio rerio NP_001019548 198 22210 Y186 S V L K R Q G Y G E G F R W L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_732717 193 21793 Y181 S V L K R Q G Y G E G F R W L
Honey Bee Apis mellifera XP_393115 193 21812 Y181 S V L K R Q G Y G E G F R W L
Nematode Worm Caenorhab. elegans Q23445 193 21690 Y182 S V L Q R Q G Y G E G I R W L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04834 193 22012 Y181 S I V R K M G Y G E G F K W V
Baker's Yeast Sacchar. cerevisiae P20606 190 21432 Y179 S V V M R N G Y L E A F Q W L
Red Bread Mold Neurospora crassa P0C583 189 21564 Y178 S V V M R Q G Y G E A I R W L
Conservation
Percent
Protein Identity: 100 88.3 99.4 98.9 N.A. 98.9 98.9 N.A. 89.9 95.4 87.8 91.9 N.A. 70.7 71.7 63.6 N.A.
Protein Similarity: 100 88.8 100 100 N.A. 100 100 N.A. 97.4 96.9 95.9 95.9 N.A. 83.3 83.8 81.8 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 93.3 100 93.3 93.3 N.A. 93.3 93.3 80 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 100 100 93.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 60.6 59 60.6
Protein Similarity: N.A. N.A. N.A. 76.2 70.2 77.2
P-Site Identity: N.A. N.A. N.A. 53.3 53.3 66.6
P-Site Similarity: N.A. N.A. N.A. 93.3 73.3 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 88 0 0 0 % F
% Gly: 0 0 0 0 0 0 100 0 94 0 88 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 0 0 0 0 0 0 0 13 0 0 0 % I
% Lys: 0 0 0 75 7 0 0 0 0 0 0 0 7 0 0 % K
% Leu: 0 0 82 0 0 0 0 0 7 0 0 0 0 0 50 % L
% Met: 0 0 0 13 0 7 0 0 0 0 0 0 0 0 44 % M
% Asn: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 7 0 88 0 0 0 0 0 0 7 0 0 % Q
% Arg: 0 0 0 7 94 0 0 0 0 0 0 0 88 0 0 % R
% Ser: 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 94 19 0 0 0 0 0 0 0 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % W
% Tyr: 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _