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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP4B1
All Species:
18.79
Human Site:
S466
Identified Species:
34.44
UniProt:
Q9Y6B7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6B7
NP_006585.2
739
83260
S466
D
F
V
E
N
V
K
S
E
T
F
P
A
V
K
Chimpanzee
Pan troglodytes
XP_001152915
739
83180
S466
D
F
V
E
N
V
K
S
E
T
F
P
A
V
K
Rhesus Macaque
Macaca mulatta
XP_001110833
739
83267
S466
D
F
V
E
N
V
K
S
E
T
F
P
A
V
K
Dog
Lupus familis
XP_540241
663
74543
E400
T
F
P
A
V
K
M
E
L
L
T
A
L
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV76
739
82600
S466
D
F
V
Q
S
V
K
S
E
T
F
P
A
V
K
Rat
Rattus norvegicus
P62944
937
104534
H474
E
S
F
L
E
G
F
H
D
E
S
T
Q
V
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508085
739
82256
A466
D
F
V
E
N
V
K
A
E
T
F
P
A
V
K
Chicken
Gallus gallus
NP_001026088
534
59115
T272
A
V
K
M
E
L
L
T
A
L
V
R
L
F
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956632
729
81136
T466
V
Y
I
D
G
L
K
T
E
L
S
A
A
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002309568
842
92984
E495
N
L
T
E
N
W
D
E
E
H
S
A
E
V
R
Maize
Zea mays
NP_001151584
841
92750
E496
S
L
V
E
N
W
D
E
E
H
S
P
E
V
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196710
841
93248
E495
N
L
I
E
N
W
E
E
E
H
S
A
E
V
R
Baker's Yeast
Sacchar. cerevisiae
P36000
726
81850
S463
N
P
E
V
L
L
Q
S
D
I
A
K
C
N
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99
84.8
N.A.
90.2
24.8
N.A.
83.3
53.8
N.A.
57.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
99.3
86.4
N.A.
94.4
45.1
N.A.
90.3
61.9
N.A.
74.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
86.6
6.6
N.A.
93.3
0
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
26.6
N.A.
100
13.3
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
31.7
31.5
N.A.
30.9
25.8
N.A.
Protein Similarity:
49.6
49.5
N.A.
49.5
47.5
N.A.
P-Site Identity:
26.6
40
N.A.
26.6
6.6
N.A.
P-Site Similarity:
40
46.6
N.A.
53.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
0
8
8
0
8
31
47
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
39
0
0
8
0
0
16
0
16
0
0
0
0
0
0
% D
% Glu:
8
0
8
54
16
0
8
31
70
8
0
0
24
0
0
% E
% Phe:
0
47
8
0
0
0
8
0
0
0
39
0
0
8
0
% F
% Gly:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
24
0
0
0
0
0
% H
% Ile:
0
0
16
0
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
8
47
0
0
0
0
8
0
0
47
% K
% Leu:
0
24
0
8
8
24
8
0
8
24
0
0
16
16
8
% L
% Met:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
24
0
0
0
54
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
8
8
0
0
0
0
0
0
0
0
47
0
0
0
% P
% Gln:
0
0
0
8
0
0
8
0
0
0
0
0
8
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
31
% R
% Ser:
8
8
0
0
8
0
0
39
0
0
39
0
0
0
0
% S
% Thr:
8
0
8
0
0
0
0
16
0
39
8
8
0
0
0
% T
% Val:
8
8
47
8
8
39
0
0
0
0
8
0
0
70
0
% V
% Trp:
0
0
0
0
0
24
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _