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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP4B1
All Species:
20.61
Human Site:
S535
Identified Species:
37.78
UniProt:
Q9Y6B7
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6B7
NP_006585.2
739
83260
S535
E
V
K
R
I
L
C
S
P
K
S
D
P
T
L
Chimpanzee
Pan troglodytes
XP_001152915
739
83180
S535
E
V
K
R
I
L
C
S
P
K
S
D
P
T
L
Rhesus Macaque
Macaca mulatta
XP_001110833
739
83267
S535
E
V
K
R
I
L
C
S
P
K
S
D
P
T
L
Dog
Lupus familis
XP_540241
663
74543
S466
C
S
P
K
S
D
P
S
L
G
L
L
E
D
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV76
739
82600
S535
K
T
K
Q
I
L
C
S
P
K
S
D
P
S
L
Rat
Rattus norvegicus
P62944
937
104534
S549
L
S
E
K
P
L
I
S
E
E
T
D
L
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508085
739
82256
S535
K
V
K
R
I
L
C
S
P
K
S
N
P
S
L
Chicken
Gallus gallus
NP_001026088
534
59115
L338
K
S
D
P
S
L
G
L
L
E
D
Q
T
E
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956632
729
81136
V532
G
I
E
E
T
R
K
V
V
T
G
P
K
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002309568
842
92984
P563
V
A
E
R
V
V
N
P
P
K
Q
A
V
S
V
Maize
Zea mays
NP_001151584
841
92750
P564
V
A
E
R
V
V
N
P
P
K
Q
A
V
S
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196710
841
93248
P563
V
A
E
R
V
V
S
P
P
K
Q
A
V
S
V
Baker's Yeast
Sacchar. cerevisiae
P36000
726
81850
A529
L
Q
S
V
L
E
L
A
T
Q
Q
T
H
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99
84.8
N.A.
90.2
24.8
N.A.
83.3
53.8
N.A.
57.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
99.3
86.4
N.A.
94.4
45.1
N.A.
90.3
61.9
N.A.
74.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
73.3
20
N.A.
80
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
93.3
46.6
N.A.
100
20
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
31.7
31.5
N.A.
30.9
25.8
N.A.
Protein Similarity:
49.6
49.5
N.A.
49.5
47.5
N.A.
P-Site Identity:
20
20
N.A.
20
6.6
N.A.
P-Site Similarity:
53.3
53.3
N.A.
53.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
0
0
0
0
0
8
0
0
0
24
0
0
0
% A
% Cys:
8
0
0
0
0
0
39
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
8
0
0
0
0
8
39
0
8
8
% D
% Glu:
24
0
39
8
0
8
0
0
8
16
0
0
8
16
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
8
0
0
8
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
8
0
0
39
0
8
0
0
0
0
0
0
8
0
% I
% Lys:
24
0
39
16
0
0
8
0
0
62
0
0
8
0
0
% K
% Leu:
16
0
0
0
8
54
8
8
16
0
8
8
8
0
47
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
16
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
8
8
8
0
8
24
62
0
0
8
39
0
0
% P
% Gln:
0
8
0
8
0
0
0
0
0
8
31
8
0
0
16
% Q
% Arg:
0
0
0
54
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
24
8
0
16
0
8
54
0
0
39
0
0
47
0
% S
% Thr:
0
8
0
0
8
0
0
0
8
8
8
8
8
24
0
% T
% Val:
24
31
0
8
24
24
0
8
8
0
0
0
24
0
24
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _