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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AP4B1 All Species: 9.09
Human Site: S676 Identified Species: 16.67
UniProt: Q9Y6B7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6B7 NP_006585.2 739 83260 S676 I A M S R A G S R P W K A Y L
Chimpanzee Pan troglodytes XP_001152915 739 83180 S676 I A M S R A G S R P W K A Y L
Rhesus Macaque Macaca mulatta XP_001110833 739 83267 T676 I A M S R A G T R P W K A Y L
Dog Lupus familis XP_540241 663 74543 A600 I A M S R A G A H P W K A Y L
Cat Felis silvestris
Mouse Mus musculus Q9WV76 739 82600 A676 I A M S K P G A Q P W K A Y L
Rat Rattus norvegicus P62944 937 104534 Q869 D T V S S K L Q N N N V Y T I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508085 739 82256 A676 I A V S K P G A Q P W K A Y L
Chicken Gallus gallus NP_001026088 534 59115 Q472 A M S K A G V Q P W K A Y F T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_956632 729 81136 A666 L A F S P A R A L P W R A Y I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002309568 842 92984 A710 L G L P A A P A P T P A P S P
Maize Zea mays NP_001151584 841 92750 A756 L S P Q G A V A L M N P Q S L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_196710 841 93248 A723 P P L L K L N A R A A L D P G
Baker's Yeast Sacchar. cerevisiae P36000 726 81850 L664 T L T T L G D L D D L F D F G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99 84.8 N.A. 90.2 24.8 N.A. 83.3 53.8 N.A. 57.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 99.3 86.4 N.A. 94.4 45.1 N.A. 90.3 61.9 N.A. 74.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 86.6 N.A. 73.3 6.6 N.A. 66.6 0 N.A. 46.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 20 N.A. 93.3 6.6 N.A. 73.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 31.7 31.5 N.A. 30.9 25.8 N.A.
Protein Similarity: 49.6 49.5 N.A. 49.5 47.5 N.A.
P-Site Identity: 6.6 13.3 N.A. 6.6 0 N.A.
P-Site Similarity: 26.6 33.3 N.A. 26.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 54 0 0 16 54 0 54 0 8 8 16 54 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 8 0 8 8 0 0 16 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 8 0 16 0 % F
% Gly: 0 8 0 0 8 16 47 0 0 0 0 0 0 0 16 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 47 0 0 0 0 0 0 0 0 0 0 0 0 0 16 % I
% Lys: 0 0 0 8 24 8 0 0 0 0 8 47 0 0 0 % K
% Leu: 24 8 16 8 8 8 8 8 16 0 8 8 0 0 54 % L
% Met: 0 8 39 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 8 8 16 0 0 0 0 % N
% Pro: 8 8 8 8 8 16 8 0 16 54 8 8 8 8 8 % P
% Gln: 0 0 0 8 0 0 0 16 16 0 0 0 8 0 0 % Q
% Arg: 0 0 0 0 31 0 8 0 31 0 0 8 0 0 0 % R
% Ser: 0 8 8 62 8 0 0 16 0 0 0 0 0 16 0 % S
% Thr: 8 8 8 8 0 0 0 8 0 8 0 0 0 8 8 % T
% Val: 0 0 16 0 0 0 16 0 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 8 54 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 16 54 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _