KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP4B1
All Species:
19.39
Human Site:
T562
Identified Species:
35.56
UniProt:
Q9Y6B7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6B7
NP_006585.2
739
83260
T562
S
W
A
S
D
F
N
T
L
V
P
V
Y
G
K
Chimpanzee
Pan troglodytes
XP_001152915
739
83180
T562
S
W
A
S
D
F
N
T
L
V
P
V
Y
G
K
Rhesus Macaque
Macaca mulatta
XP_001110833
739
83267
T562
S
W
A
S
D
F
N
T
L
V
P
V
Y
G
K
Dog
Lupus familis
XP_540241
663
74543
G493
N
T
L
V
P
V
Y
G
K
A
R
W
A
A
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV76
739
82600
T562
S
W
A
S
D
F
N
T
L
A
P
V
Y
G
K
Rat
Rattus norvegicus
P62944
937
104534
K576
S
L
A
S
V
Y
H
K
P
P
N
A
F
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508085
739
82256
T562
S
W
A
S
D
F
N
T
L
M
P
V
Y
G
K
Chicken
Gallus gallus
NP_001026088
534
59115
R365
A
P
I
Y
G
K
A
R
W
A
L
V
T
A
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956632
729
81136
I559
P
V
S
Q
W
V
S
I
F
N
T
L
G
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002309568
842
92984
L590
I
F
D
E
F
N
S
L
S
V
V
Y
Q
K
P
Maize
Zea mays
NP_001151584
841
92750
L591
I
F
D
E
F
N
S
L
S
V
V
Y
Q
K
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196710
841
93248
L590
V
F
D
E
F
N
S
L
S
V
I
Y
Q
K
P
Baker's Yeast
Sacchar. cerevisiae
P36000
726
81850
S556
L
S
M
P
N
N
E
S
L
V
N
D
L
C
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99
84.8
N.A.
90.2
24.8
N.A.
83.3
53.8
N.A.
57.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
99.3
86.4
N.A.
94.4
45.1
N.A.
90.3
61.9
N.A.
74.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
93.3
20
N.A.
93.3
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
93.3
46.6
N.A.
100
13.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
31.7
31.5
N.A.
30.9
25.8
N.A.
Protein Similarity:
49.6
49.5
N.A.
49.5
47.5
N.A.
P-Site Identity:
6.6
6.6
N.A.
6.6
13.3
N.A.
P-Site Similarity:
20
20
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
47
0
0
0
8
0
0
24
0
8
8
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
24
0
39
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
0
0
0
24
0
0
8
0
0
0
0
0
0
0
8
% E
% Phe:
0
24
0
0
24
39
0
0
8
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
8
0
0
8
0
0
0
0
8
39
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% H
% Ile:
16
0
8
0
0
0
0
8
0
0
8
0
0
0
8
% I
% Lys:
0
0
0
0
0
8
0
8
8
0
0
0
0
24
39
% K
% Leu:
8
8
8
0
0
0
0
24
47
0
8
8
8
0
8
% L
% Met:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
31
39
0
0
8
16
0
0
0
0
% N
% Pro:
8
8
0
8
8
0
0
0
8
8
39
0
0
8
24
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
0
24
0
8
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% R
% Ser:
47
8
8
47
0
0
31
8
24
0
0
0
0
0
0
% S
% Thr:
0
8
0
0
0
0
0
39
0
0
8
0
8
0
0
% T
% Val:
8
8
0
8
8
16
0
0
0
54
16
47
0
8
0
% V
% Trp:
0
39
0
0
8
0
0
0
8
0
0
8
0
0
0
% W
% Tyr:
0
0
0
8
0
8
8
0
0
0
0
24
39
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _