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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP4B1
All Species:
10.3
Human Site:
T591
Identified Species:
18.89
UniProt:
Q9Y6B7
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6B7
NP_006585.2
739
83260
T591
C
D
P
E
L
P
K
T
S
S
F
A
A
S
G
Chimpanzee
Pan troglodytes
XP_001152915
739
83180
T591
C
G
P
E
L
P
K
T
S
S
F
A
A
S
G
Rhesus Macaque
Macaca mulatta
XP_001110833
739
83267
T591
C
G
P
E
L
P
K
T
S
S
F
A
A
S
G
Dog
Lupus familis
XP_540241
663
74543
S522
N
T
A
S
F
A
S
S
G
P
L
I
P
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV76
739
82600
N591
H
R
L
E
L
P
H
N
A
S
F
A
T
S
G
Rat
Rattus norvegicus
P62944
937
104534
S605
G
S
T
D
A
G
D
S
P
V
G
T
T
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508085
739
82256
A591
Q
A
P
N
A
P
R
A
A
A
F
A
S
P
G
Chicken
Gallus gallus
NP_001026088
534
59115
S394
S
G
N
R
G
T
G
S
L
I
S
E
G
S
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956632
729
81136
A588
S
E
H
T
D
D
T
A
D
T
E
L
L
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002309568
842
92984
L619
F
S
D
E
L
G
N
L
A
I
R
T
E
S
D
Maize
Zea mays
NP_001151584
841
92750
L620
Y
S
E
D
L
T
G
L
T
E
D
P
E
N
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196710
841
93248
I619
F
S
D
E
V
G
N
I
S
I
T
P
E
A
S
Baker's Yeast
Sacchar. cerevisiae
P36000
726
81850
L585
P
E
V
L
E
K
L
L
M
E
L
G
T
I
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99
84.8
N.A.
90.2
24.8
N.A.
83.3
53.8
N.A.
57.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
99.3
86.4
N.A.
94.4
45.1
N.A.
90.3
61.9
N.A.
74.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
0
N.A.
53.3
0
N.A.
33.3
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
6.6
N.A.
60
20
N.A.
60
13.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
31.7
31.5
N.A.
30.9
25.8
N.A.
Protein Similarity:
49.6
49.5
N.A.
49.5
47.5
N.A.
P-Site Identity:
20
6.6
N.A.
13.3
0
N.A.
P-Site Similarity:
26.6
26.6
N.A.
26.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
16
8
0
16
24
8
0
39
24
8
8
% A
% Cys:
24
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
16
16
8
8
8
0
8
0
8
0
0
0
8
% D
% Glu:
0
16
8
47
8
0
0
0
0
16
8
8
24
8
16
% E
% Phe:
16
0
0
0
8
0
0
0
0
0
39
0
0
0
0
% F
% Gly:
8
24
0
0
8
24
16
0
8
0
8
8
8
0
39
% G
% His:
8
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
24
0
8
0
8
0
% I
% Lys:
0
0
0
0
0
8
24
0
0
0
0
0
0
0
8
% K
% Leu:
0
0
8
8
47
0
8
24
8
0
16
8
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
8
0
8
8
0
0
16
8
0
0
0
0
0
8
0
% N
% Pro:
8
0
31
0
0
39
0
0
8
8
0
16
8
8
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
8
0
0
8
0
0
0
8
0
0
0
0
% R
% Ser:
16
31
0
8
0
0
8
24
31
31
8
0
8
47
16
% S
% Thr:
0
8
8
8
0
16
8
24
8
8
8
16
24
16
0
% T
% Val:
0
0
8
0
8
0
0
0
0
8
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _