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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP4B1
All Species:
32.73
Human Site:
Y355
Identified Species:
60
UniProt:
Q9Y6B7
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6B7
NP_006585.2
739
83260
Y355
V
L
E
E
L
R
G
Y
C
T
D
V
S
A
D
Chimpanzee
Pan troglodytes
XP_001152915
739
83180
Y355
V
L
E
E
L
R
G
Y
C
T
D
V
S
A
D
Rhesus Macaque
Macaca mulatta
XP_001110833
739
83267
Y355
V
L
E
E
L
R
G
Y
C
T
D
V
S
A
D
Dog
Lupus familis
XP_540241
663
74543
A300
I
F
A
I
G
G
I
A
R
T
Y
T
D
Q
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV76
739
82600
Y355
V
L
E
E
L
R
G
Y
C
T
D
V
S
A
D
Rat
Rattus norvegicus
P62944
937
104534
Y361
V
L
A
E
L
K
E
Y
A
T
E
V
D
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508085
739
82256
Y355
V
L
E
E
L
K
G
Y
C
T
D
V
S
A
D
Chicken
Gallus gallus
NP_001026088
534
59115
Y172
I
G
S
I
A
R
T
Y
T
E
Q
C
V
G
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956632
729
81136
Y355
V
L
E
E
M
K
S
Y
C
T
D
V
S
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002309568
842
92984
Y381
I
V
T
E
L
C
E
Y
A
A
N
V
D
I
P
Maize
Zea mays
NP_001151584
841
92750
Y382
I
V
T
E
L
C
E
Y
A
G
N
V
D
V
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196710
841
93248
Y381
I
V
T
E
L
C
E
Y
A
A
N
V
D
I
A
Baker's Yeast
Sacchar. cerevisiae
P36000
726
81850
P360
I
L
V
R
L
V
D
P
S
N
L
K
Q
C
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99
84.8
N.A.
90.2
24.8
N.A.
83.3
53.8
N.A.
57.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
99.3
86.4
N.A.
94.4
45.1
N.A.
90.3
61.9
N.A.
74.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
100
53.3
N.A.
93.3
13.3
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
66.6
N.A.
100
20
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
31.7
31.5
N.A.
30.9
25.8
N.A.
Protein Similarity:
49.6
49.5
N.A.
49.5
47.5
N.A.
P-Site Identity:
26.6
26.6
N.A.
26.6
13.3
N.A.
P-Site Similarity:
46.6
46.6
N.A.
46.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
8
0
0
8
31
16
0
0
0
47
8
% A
% Cys:
0
0
0
0
0
24
0
0
47
0
0
8
0
8
8
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
47
0
39
0
47
% D
% Glu:
0
0
47
77
0
0
31
0
0
8
8
0
0
0
8
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
8
8
39
0
0
8
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
47
0
0
16
0
0
8
0
0
0
0
0
0
16
8
% I
% Lys:
0
0
0
0
0
24
0
0
0
0
0
8
0
0
0
% K
% Leu:
0
62
0
0
77
0
0
0
0
0
8
0
0
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
24
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
16
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
0
8
8
0
% Q
% Arg:
0
0
0
8
0
39
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
0
8
0
0
0
8
0
8
0
0
0
47
0
0
% S
% Thr:
0
0
24
0
0
0
8
0
8
62
0
8
0
0
8
% T
% Val:
54
24
8
0
0
8
0
0
0
0
0
77
8
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
85
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _