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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP4B1
All Species:
11.82
Human Site:
Y630
Identified Species:
21.67
UniProt:
Q9Y6B7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6B7
NP_006585.2
739
83260
Y630
N
R
Q
L
T
A
D
Y
F
E
K
T
W
L
S
Chimpanzee
Pan troglodytes
XP_001152915
739
83180
Y630
N
R
Q
L
T
A
D
Y
F
E
K
T
W
L
S
Rhesus Macaque
Macaca mulatta
XP_001110833
739
83267
Y630
N
R
Q
L
T
A
D
Y
F
E
K
T
W
L
S
Dog
Lupus familis
XP_540241
663
74543
T558
T
A
E
Y
F
E
K
T
W
F
S
L
K
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV76
739
82600
C630
N
L
Q
L
T
A
E
C
F
E
K
T
W
L
S
Rat
Rattus norvegicus
P62944
937
104534
M795
L
N
T
L
G
P
V
M
K
M
E
P
L
N
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508085
739
82256
Q630
P
G
Q
L
T
A
E
Q
F
E
R
S
W
L
S
Chicken
Gallus gallus
NP_001026088
534
59115
W430
A
E
Q
F
E
K
T
W
L
S
L
D
I
S
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956632
729
81136
Q624
V
S
P
E
A
F
E
Q
M
W
Q
Q
L
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002309568
842
92984
Y659
S
G
T
N
G
S
A
Y
T
A
P
L
Y
D
T
Maize
Zea mays
NP_001151584
841
92750
P680
S
L
I
S
S
Q
T
P
A
E
T
S
L
V
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196710
841
93248
I674
S
L
E
S
S
S
N
I
T
S
Q
M
Q
E
L
Baker's Yeast
Sacchar. cerevisiae
P36000
726
81850
E622
G
K
H
I
E
E
L
E
S
M
A
K
N
E
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99
84.8
N.A.
90.2
24.8
N.A.
83.3
53.8
N.A.
57.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
99.3
86.4
N.A.
94.4
45.1
N.A.
90.3
61.9
N.A.
74.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
80
6.6
N.A.
60
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
86.6
20
N.A.
80
13.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
31.7
31.5
N.A.
30.9
25.8
N.A.
Protein Similarity:
49.6
49.5
N.A.
49.5
47.5
N.A.
P-Site Identity:
6.6
6.6
N.A.
0
0
N.A.
P-Site Similarity:
33.3
40
N.A.
40
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
8
39
8
0
8
8
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
0
24
0
0
0
0
8
0
8
0
% D
% Glu:
0
8
16
8
16
16
24
8
0
47
8
0
0
24
0
% E
% Phe:
0
0
0
8
8
8
0
0
39
8
0
0
0
0
0
% F
% Gly:
8
16
0
0
16
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
8
0
0
0
8
0
0
0
0
8
0
8
% I
% Lys:
0
8
0
0
0
8
8
0
8
0
31
8
8
0
0
% K
% Leu:
8
24
0
47
0
0
8
0
8
0
8
16
24
39
8
% L
% Met:
0
0
0
0
0
0
0
8
8
16
0
8
0
0
0
% M
% Asn:
31
8
0
8
0
0
8
0
0
0
0
0
8
8
16
% N
% Pro:
8
0
8
0
0
8
0
8
0
0
8
8
0
0
0
% P
% Gln:
0
0
47
0
0
8
0
16
0
0
16
8
8
0
0
% Q
% Arg:
0
24
0
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
24
8
0
16
16
16
0
0
8
16
8
16
0
8
39
% S
% Thr:
8
0
16
0
39
0
16
8
16
0
8
31
0
0
8
% T
% Val:
8
0
0
0
0
0
8
0
0
0
0
0
0
16
8
% V
% Trp:
0
0
0
0
0
0
0
8
8
8
0
0
39
0
0
% W
% Tyr:
0
0
0
8
0
0
0
31
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _