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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP4B1
All Species:
26.97
Human Site:
Y682
Identified Species:
49.44
UniProt:
Q9Y6B7
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6B7
NP_006585.2
739
83260
Y682
G
S
R
P
W
K
A
Y
L
S
A
Q
D
D
T
Chimpanzee
Pan troglodytes
XP_001152915
739
83180
Y682
G
S
R
P
W
K
A
Y
L
S
A
Q
D
D
T
Rhesus Macaque
Macaca mulatta
XP_001110833
739
83267
Y682
G
T
R
P
W
K
A
Y
L
S
A
Q
D
D
T
Dog
Lupus familis
XP_540241
663
74543
Y606
G
A
H
P
W
K
A
Y
L
S
A
Q
D
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV76
739
82600
Y682
G
A
Q
P
W
K
A
Y
L
S
A
Q
D
G
T
Rat
Rattus norvegicus
P62944
937
104534
T875
L
Q
N
N
N
V
Y
T
I
A
K
R
N
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508085
739
82256
Y682
G
A
Q
P
W
K
A
Y
L
G
A
S
D
D
T
Chicken
Gallus gallus
NP_001026088
534
59115
F478
V
Q
P
W
K
A
Y
F
T
A
Q
D
D
S
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956632
729
81136
Y672
R
A
L
P
W
R
A
Y
I
Y
S
R
G
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002309568
842
92984
S716
P
A
P
T
P
A
P
S
P
P
S
L
K
L
N
Maize
Zea mays
NP_001151584
841
92750
S762
V
A
L
M
N
P
Q
S
L
I
R
H
M
Q
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196710
841
93248
P729
N
A
R
A
A
L
D
P
G
A
F
Q
Q
K
W
Baker's Yeast
Sacchar. cerevisiae
P36000
726
81850
F670
D
L
D
D
L
F
D
F
G
P
S
E
D
A
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99
84.8
N.A.
90.2
24.8
N.A.
83.3
53.8
N.A.
57.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
99.3
86.4
N.A.
94.4
45.1
N.A.
90.3
61.9
N.A.
74.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
86.6
N.A.
80
0
N.A.
73.3
6.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
26.6
N.A.
86.6
20
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
31.7
31.5
N.A.
30.9
25.8
N.A.
Protein Similarity:
49.6
49.5
N.A.
49.5
47.5
N.A.
P-Site Identity:
0
6.6
N.A.
13.3
13.3
N.A.
P-Site Similarity:
13.3
20
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
54
0
8
8
16
54
0
0
24
47
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
8
0
0
16
0
0
0
0
8
62
39
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% E
% Phe:
0
0
0
0
0
8
0
16
0
0
8
0
0
0
0
% F
% Gly:
47
0
0
0
0
0
0
0
16
8
0
0
8
8
16
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
16
8
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
47
0
0
0
0
8
0
8
8
0
% K
% Leu:
8
8
16
0
8
8
0
0
54
0
0
8
0
8
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
8
0
8
8
16
0
0
0
0
0
0
0
8
0
8
% N
% Pro:
8
0
16
54
8
8
8
8
8
16
0
0
0
0
0
% P
% Gln:
0
16
16
0
0
0
8
0
0
0
8
47
8
8
0
% Q
% Arg:
8
0
31
0
0
8
0
0
0
0
8
16
0
0
0
% R
% Ser:
0
16
0
0
0
0
0
16
0
39
24
8
0
16
8
% S
% Thr:
0
8
0
8
0
0
0
8
8
0
0
0
0
0
54
% T
% Val:
16
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
8
54
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
16
54
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _