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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SELK All Species: 13.33
Human Site: S12 Identified Species: 29.33
UniProt: Q9Y6D0 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6D0 NP_067060.2 94 10645 S12 S N G Q V L D S R S Q S P W R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9JLJ1 94 10473 S12 S N G Q V L D S R N Q S P W R
Rat Rattus norvegicus P59798 94 10457 S12 S N G Q V L D S R N Q S P W R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506545 91 10113 G12 S N G H V L N G Q N R S L W S
Chicken Gallus gallus NP_001020612 95 10353 N12 S N G Q V L D N R S R A P W S
Frog Xenopus laevis Q641S4 95 10249 G12 S N G Q V L D G Q S R S P W R
Zebra Danio Brachydanio rerio Q66I79 94 9985 S12 S N G Q V L D S R S R S P W S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_625244 89 10054 G13 N D G S V L C G T P L Y L K V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785269 100 10691 D12 S Q S G Q V M D S R S P W R L
Poplar Tree Populus trichocarpa XP_002307425 100 10705 Q12 E R G V V K S Q R S I W R L R
Maize Zea mays NP_001143751 111 11513 K12 E R G V L K D K R T I W R L S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. N.A. N.A. 91.4 93.6 N.A. 62.7 70.5 67.3 69.1 N.A. N.A. 35.1 N.A. 47
Protein Similarity: 100 N.A. N.A. N.A. N.A. 95.7 94.6 N.A. 77.6 82.1 81 78.7 N.A. N.A. 51 N.A. 58
P-Site Identity: 100 N.A. N.A. N.A. N.A. 93.3 93.3 N.A. 46.6 73.3 80 86.6 N.A. N.A. 20 N.A. 6.6
P-Site Similarity: 100 N.A. N.A. N.A. N.A. 100 100 N.A. 73.3 93.3 93.3 93.3 N.A. N.A. 33.3 N.A. 13.3
Percent
Protein Identity: 35 30.6 N.A. N.A. N.A. N.A.
Protein Similarity: 52 45 N.A. N.A. N.A. N.A.
P-Site Identity: 33.3 20 N.A. N.A. N.A. N.A.
P-Site Similarity: 33.3 33.3 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 64 10 0 0 0 0 0 0 0 % D
% Glu: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 91 10 0 0 0 28 0 0 0 0 0 0 0 % G
% His: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 19 0 0 0 0 % I
% Lys: 0 0 0 0 0 19 0 10 0 0 0 0 0 10 0 % K
% Leu: 0 0 0 0 10 73 0 0 0 0 10 0 19 19 10 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 10 64 0 0 0 0 10 10 0 28 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 10 0 10 55 0 0 % P
% Gln: 0 10 0 55 10 0 0 10 19 0 28 0 0 0 0 % Q
% Arg: 0 19 0 0 0 0 0 0 64 10 37 0 19 10 46 % R
% Ser: 73 0 10 10 0 0 10 37 10 46 10 55 0 0 37 % S
% Thr: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % T
% Val: 0 0 0 19 82 10 0 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 19 10 64 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _