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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAD1L1
All Species:
29.39
Human Site:
S247
Identified Species:
64.67
UniProt:
Q9Y6D9
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6D9
NP_001013858.1
718
83067
S247
A
I
V
K
N
M
K
S
E
L
V
R
L
P
R
Chimpanzee
Pan troglodytes
XP_518933
718
83078
S247
A
I
V
K
N
M
K
S
E
L
V
R
L
P
R
Rhesus Macaque
Macaca mulatta
XP_001102100
956
108383
S247
A
I
V
K
N
M
K
S
E
L
V
R
L
P
R
Dog
Lupus familis
XP_852066
833
95008
S363
S
V
V
K
N
M
K
S
E
L
M
R
L
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTX8
717
83523
S247
A
V
V
K
S
M
K
S
E
L
M
R
M
P
R
Rat
Rattus norvegicus
NP_001102857
717
83311
S247
A
V
V
K
S
M
K
S
E
L
L
R
L
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425231
717
83910
T247
V
I
V
K
N
M
K
T
E
L
A
R
F
P
K
Frog
Xenopus laevis
P10999
583
67273
E159
S
G
K
R
G
L
E
E
Q
L
Q
E
Q
R
A
Zebra Danio
Brachydanio rerio
NP_957206
323
37683
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796080
709
81997
S232
V
V
A
R
A
V
Q
S
D
V
Q
K
V
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001151757
716
81232
E249
S
E
A
K
L
L
N
E
Q
L
T
N
L
K
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
73.1
72.3
N.A.
81
83
N.A.
N.A.
69.9
20.6
27.9
N.A.
N.A.
N.A.
N.A.
33.1
Protein Similarity:
100
99.5
73.8
80.1
N.A.
90.8
92.1
N.A.
N.A.
84.6
40.5
37.7
N.A.
N.A.
N.A.
N.A.
59.3
P-Site Identity:
100
100
100
73.3
N.A.
73.3
80
N.A.
N.A.
66.6
6.6
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
80
40
0
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
23.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
46.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
46
0
19
0
10
0
0
0
0
0
10
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
0
10
19
64
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
10
0
0
10
0
0
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
37
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
73
0
0
64
0
0
0
0
10
0
10
37
% K
% Leu:
0
0
0
0
10
19
0
0
0
82
10
0
55
0
0
% L
% Met:
0
0
0
0
0
64
0
0
0
0
19
0
10
0
0
% M
% Asn:
0
0
0
0
46
0
10
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
64
0
% P
% Gln:
0
0
0
0
0
0
10
0
19
0
19
0
10
0
0
% Q
% Arg:
0
0
0
19
0
0
0
0
0
0
0
64
0
10
46
% R
% Ser:
28
0
0
0
19
0
0
64
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% T
% Val:
19
37
64
0
0
10
0
0
0
10
28
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _