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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAD1L1
All Species:
23.94
Human Site:
S597
Identified Species:
52.67
UniProt:
Q9Y6D9
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6D9
NP_001013858.1
718
83067
S597
A
A
A
A
S
L
P
S
S
K
E
V
A
E
L
Chimpanzee
Pan troglodytes
XP_518933
718
83078
S597
A
A
A
A
S
L
P
S
S
K
E
V
A
E
L
Rhesus Macaque
Macaca mulatta
XP_001102100
956
108383
S597
A
A
A
A
S
L
P
S
S
K
E
V
A
E
L
Dog
Lupus familis
XP_852066
833
95008
S712
E
A
A
A
G
L
P
S
S
K
E
V
A
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTX8
717
83523
S596
E
A
A
S
S
L
P
S
S
K
E
V
A
E
L
Rat
Rattus norvegicus
NP_001102857
717
83311
S596
E
A
A
S
S
L
P
S
S
K
E
V
A
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425231
717
83910
S596
E
G
V
G
S
F
Q
S
P
Q
E
V
A
E
L
Frog
Xenopus laevis
P10999
583
67273
F463
L
N
N
T
E
E
D
F
S
L
H
G
W
V
V
Zebra Danio
Brachydanio rerio
NP_957206
323
37683
Q203
T
L
I
I
P
P
S
Q
E
I
L
D
L
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796080
709
81997
Q589
A
N
R
I
G
E
E
Q
T
R
A
V
Q
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001151757
716
81232
L595
I
A
E
K
L
A
Q
L
K
N
Q
I
A
T
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
73.1
72.3
N.A.
81
83
N.A.
N.A.
69.9
20.6
27.9
N.A.
N.A.
N.A.
N.A.
33.1
Protein Similarity:
100
99.5
73.8
80.1
N.A.
90.8
92.1
N.A.
N.A.
84.6
40.5
37.7
N.A.
N.A.
N.A.
N.A.
59.3
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
N.A.
46.6
6.6
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
N.A.
53.3
13.3
0
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
23.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
46.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
37
64
55
37
0
10
0
0
0
0
10
0
73
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
10
0
10
0
% D
% Glu:
37
0
10
0
10
19
10
0
10
0
64
0
0
64
0
% E
% Phe:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
10
19
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
10
0
10
19
0
0
0
0
0
10
0
10
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
10
55
0
0
0
0
10
% K
% Leu:
10
10
0
0
10
55
0
10
0
10
10
0
10
0
73
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
19
10
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
10
55
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
19
19
0
10
10
0
10
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
10
0
0
0
10
0
% R
% Ser:
0
0
0
19
55
0
10
64
64
0
0
0
0
0
0
% S
% Thr:
10
0
0
10
0
0
0
0
10
0
0
0
0
10
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
73
0
10
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _