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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BZW2 All Species: 31.21
Human Site: T10 Identified Species: 57.22
UniProt: Q9Y6E2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6E2 NP_001153239.1 419 48162 T10 K H Q K P V L T G Q R F K T R
Chimpanzee Pan troglodytes XP_518982 477 54244 P68 T N R R S P Q P C A S S L P P
Rhesus Macaque Macaca mulatta XP_001104484 580 65864 P171 T N R R S P Q P C A S S L P P
Dog Lupus familis XP_862408 378 43352
Cat Felis silvestris
Mouse Mus musculus Q91VK1 419 48045 T10 K H Q K P V L T G Q R F K T R
Rat Rattus norvegicus Q9WTT7 419 48031 T10 K H Q K P V L T G Q R F K T R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505311 421 48348 S28 R G R R G G R S P R P R G F P
Chicken Gallus gallus Q5ZL42 414 47824 T10 K N Q K P V L T G Q R F K T R
Frog Xenopus laevis Q8AVM7 419 48119 S12 K Q Q K P T L S G Q R F K T R
Zebra Danio Brachydanio rerio Q1LUC1 421 48306 T12 K Q Q K P V L T G Q R F K T R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VNE2 422 49206 S11 K T E R P V L S G Q R I K T R
Honey Bee Apis mellifera XP_395256 420 48465 S11 K I E K P I L S G Q R I K T R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32501 712 81143 L12 K G Q K K S G L G N H G K N S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.9 71.2 90.2 N.A. 99 98.8 N.A. 55.3 92.3 71.1 84.3 N.A. 50 52.3 N.A. N.A.
Protein Similarity: 100 87.4 71.9 90.2 N.A. 99.5 99.5 N.A. 70.5 95.6 87.5 94.5 N.A. 72.7 73.5 N.A. N.A.
P-Site Identity: 100 0 0 0 N.A. 100 100 N.A. 0 93.3 80 93.3 N.A. 66.6 66.6 N.A. N.A.
P-Site Similarity: 100 20 20 0 N.A. 100 100 N.A. 33.3 100 86.6 93.3 N.A. 86.6 86.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 33.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 16 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 16 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 16 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 47 0 8 0 % F
% Gly: 0 16 0 0 8 8 8 0 70 0 0 8 8 0 0 % G
% His: 0 24 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 8 0 0 0 8 0 0 0 0 0 16 0 0 0 % I
% Lys: 70 0 0 62 8 0 0 0 0 0 0 0 70 0 0 % K
% Leu: 0 0 0 0 0 0 62 8 0 0 0 0 16 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 24 0 0 0 0 0 0 0 8 0 0 0 8 0 % N
% Pro: 0 0 0 0 62 16 0 16 8 0 8 0 0 16 24 % P
% Gln: 0 16 54 0 0 0 16 0 0 62 0 0 0 0 0 % Q
% Arg: 8 0 24 31 0 0 8 0 0 8 62 8 0 0 62 % R
% Ser: 0 0 0 0 16 8 0 31 0 0 16 16 0 0 8 % S
% Thr: 16 8 0 0 0 8 0 39 0 0 0 0 0 62 0 % T
% Val: 0 0 0 0 0 47 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _