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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BZW2
All Species:
31.21
Human Site:
Y349
Identified Species:
57.22
UniProt:
Q9Y6E2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6E2
NP_001153239.1
419
48162
Y349
L
L
Q
K
V
Q
E
Y
C
Y
D
N
I
H
F
Chimpanzee
Pan troglodytes
XP_518982
477
54244
Y407
L
L
Q
K
V
Q
E
Y
C
Y
D
N
I
H
F
Rhesus Macaque
Macaca mulatta
XP_001104484
580
65864
Y510
L
L
Q
K
V
Q
E
Y
C
Y
D
N
I
H
F
Dog
Lupus familis
XP_862408
378
43352
E316
K
K
E
E
L
V
A
E
Q
A
L
K
H
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q91VK1
419
48045
Y349
L
L
Q
K
V
Q
E
Y
C
Y
D
N
I
H
F
Rat
Rattus norvegicus
Q9WTT7
419
48031
Y349
L
L
Q
K
V
Q
E
Y
C
Y
D
N
I
H
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505311
421
48348
E358
S
S
V
M
S
T
V
E
W
N
K
K
E
E
L
Chicken
Gallus gallus
Q5ZL42
414
47824
Y349
L
L
Q
K
V
Q
E
Y
C
Y
D
N
I
H
F
Frog
Xenopus laevis
Q8AVM7
419
48119
Y348
L
L
L
K
I
Q
E
Y
C
Y
D
N
I
H
F
Zebra Danio
Brachydanio rerio
Q1LUC1
421
48306
Y351
L
L
L
K
I
Q
E
Y
C
Y
D
N
I
H
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VNE2
422
49206
F349
L
I
L
K
V
Q
E
F
C
Y
E
N
M
N
F
Honey Bee
Apis mellifera
XP_395256
420
48465
F350
L
I
L
K
V
Q
E
F
C
Y
E
N
M
N
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32501
712
81143
F545
S
E
F
E
D
E
D
F
E
K
E
G
I
A
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
71.2
90.2
N.A.
99
98.8
N.A.
55.3
92.3
71.1
84.3
N.A.
50
52.3
N.A.
N.A.
Protein Similarity:
100
87.4
71.9
90.2
N.A.
99.5
99.5
N.A.
70.5
95.6
87.5
94.5
N.A.
72.7
73.5
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
0
100
86.6
86.6
N.A.
60
60
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
0
100
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
8
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
77
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
8
0
0
0
62
0
0
0
0
% D
% Glu:
0
8
8
16
0
8
77
16
8
0
24
0
8
8
0
% E
% Phe:
0
0
8
0
0
0
0
24
0
0
0
0
0
0
77
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
62
0
% H
% Ile:
0
16
0
0
16
0
0
0
0
0
0
0
70
0
0
% I
% Lys:
8
8
0
77
0
0
0
0
0
8
8
16
0
0
8
% K
% Leu:
77
62
31
0
8
0
0
0
0
0
8
0
0
8
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
16
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
77
0
16
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
47
0
0
77
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
16
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% T
% Val:
0
0
8
0
62
8
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
62
0
77
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _