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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PARP3
All Species:
8.79
Human Site:
S145
Identified Species:
19.33
UniProt:
Q9Y6F1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6F1
NP_005476.3
533
60070
S145
A
E
R
D
H
F
V
S
H
P
G
K
Y
T
L
Chimpanzee
Pan troglodytes
XP_001170254
532
60080
S144
A
E
R
D
H
F
V
S
H
P
G
K
Y
T
L
Rhesus Macaque
Macaca mulatta
XP_001087761
503
56366
A144
A
E
R
D
R
F
V
A
H
P
G
K
Y
T
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88554
559
63378
K176
E
D
R
E
N
F
E
K
V
P
G
K
Y
D
M
Rat
Rattus norvegicus
NP_001008329
526
58850
A142
E
E
R
D
H
F
V
A
H
P
N
K
Y
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520908
193
21776
Chicken
Gallus gallus
Frog
Xenopus laevis
P31669
998
111108
K212
A
T
K
K
K
I
K
K
E
K
E
K
E
S
K
Zebra Danio
Brachydanio rerio
NP_956795
531
59822
S145
S
D
R
E
N
F
V
S
H
S
G
K
Y
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785135
532
59769
P143
E
N
R
A
N
F
E
P
K
A
G
K
Y
T
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O50017
653
72977
C271
S
D
R
K
N
F
K
C
Y
A
K
K
Y
T
W
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q11207
637
72157
P250
S
D
R
K
E
F
I
P
H
P
K
S
Y
T
W
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97
87.8
N.A.
N.A.
34.3
80.6
N.A.
27.9
N.A.
20.8
55.1
N.A.
N.A.
N.A.
N.A.
50.2
Protein Similarity:
100
98.3
89.4
N.A.
N.A.
52.4
86.8
N.A.
31.7
N.A.
33.4
72.9
N.A.
N.A.
N.A.
N.A.
65.6
P-Site Identity:
100
100
86.6
N.A.
N.A.
40
80
N.A.
0
N.A.
13.3
66.6
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
93.3
N.A.
N.A.
66.6
86.6
N.A.
0
N.A.
26.6
93.3
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
29.7
N.A.
31.2
N.A.
N.A.
Protein Similarity:
N.A.
46.5
N.A.
47.5
N.A.
N.A.
P-Site Identity:
N.A.
33.3
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
60
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
37
0
0
10
0
0
0
19
0
19
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
37
0
37
0
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
28
37
0
19
10
0
19
0
10
0
10
0
10
0
0
% E
% Phe:
0
0
0
0
0
82
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
55
0
0
0
0
% G
% His:
0
0
0
0
28
0
0
0
55
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
28
10
0
19
19
10
10
19
82
0
0
10
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
55
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
10
0
0
37
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
19
0
55
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
82
0
10
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
28
0
0
0
0
0
0
28
0
10
0
10
0
10
0
% S
% Thr:
0
10
0
0
0
0
0
0
0
0
0
0
0
73
0
% T
% Val:
0
0
0
0
0
0
46
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
82
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _