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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PARP3
All Species:
12.12
Human Site:
S275
Identified Species:
26.67
UniProt:
Q9Y6F1
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6F1
NP_005476.3
533
60070
S275
S
Q
P
P
P
I
N
S
P
E
L
L
Q
A
K
Chimpanzee
Pan troglodytes
XP_001170254
532
60080
S274
S
Q
P
P
P
I
N
S
P
E
L
L
Q
A
K
Rhesus Macaque
Macaca mulatta
XP_001087761
503
56366
Y257
E
E
L
S
S
H
F
Y
T
V
I
P
H
N
F
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88554
559
63378
T299
S
I
P
P
V
I
R
T
E
K
E
L
S
D
K
Rat
Rattus norvegicus
NP_001008329
526
58850
S268
S
R
P
P
P
I
N
S
P
D
I
L
Q
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520908
193
21776
Chicken
Gallus gallus
Frog
Xenopus laevis
P31669
998
111108
N737
K
K
P
P
L
L
N
N
L
E
Y
I
Q
A
K
Zebra Danio
Brachydanio rerio
NP_956795
531
59822
D274
N
R
P
P
V
I
S
D
D
S
V
L
Q
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785135
532
59769
D272
K
I
P
P
V
I
D
D
A
E
K
I
Q
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O50017
653
72977
I392
R
K
M
R
E
F
I
I
D
T
P
Q
K
L
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q11207
637
72157
I377
K
K
M
S
Q
F
V
I
D
T
P
Q
K
L
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97
87.8
N.A.
N.A.
34.3
80.6
N.A.
27.9
N.A.
20.8
55.1
N.A.
N.A.
N.A.
N.A.
50.2
Protein Similarity:
100
98.3
89.4
N.A.
N.A.
52.4
86.8
N.A.
31.7
N.A.
33.4
72.9
N.A.
N.A.
N.A.
N.A.
65.6
P-Site Identity:
100
100
0
N.A.
N.A.
40
80
N.A.
0
N.A.
46.6
40
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
13.3
N.A.
N.A.
53.3
100
N.A.
0
N.A.
73.3
73.3
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
29.7
N.A.
31.2
N.A.
N.A.
Protein Similarity:
N.A.
46.5
N.A.
47.5
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
0
0
46
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
19
28
10
0
0
0
10
0
% D
% Glu:
10
10
0
0
10
0
0
0
10
37
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
19
10
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
19
0
0
0
55
10
19
0
0
19
19
0
0
0
% I
% Lys:
28
28
0
0
0
0
0
0
0
10
10
0
19
0
82
% K
% Leu:
0
0
10
0
10
10
0
0
10
0
19
46
0
19
0
% L
% Met:
0
0
19
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
37
10
0
0
0
0
0
10
0
% N
% Pro:
0
0
64
64
28
0
0
0
28
0
19
10
0
0
0
% P
% Gln:
0
19
0
0
10
0
0
0
0
0
0
19
55
0
0
% Q
% Arg:
10
19
0
10
0
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
37
0
0
19
10
0
10
28
0
10
0
0
10
10
0
% S
% Thr:
0
0
0
0
0
0
0
10
10
19
0
0
0
0
0
% T
% Val:
0
0
0
0
28
0
10
0
0
10
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _