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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PARP3
All Species:
12.42
Human Site:
S458
Identified Species:
27.33
UniProt:
Q9Y6F1
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6F1
NP_005476.3
533
60070
S458
H
I
N
T
D
N
P
S
L
K
S
P
P
P
G
Chimpanzee
Pan troglodytes
XP_001170254
532
60080
S457
H
I
N
T
D
N
P
S
L
K
S
P
P
P
G
Rhesus Macaque
Macaca mulatta
XP_001087761
503
56366
S428
H
I
T
T
D
K
P
S
L
K
S
P
P
P
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88554
559
63378
K480
E
L
L
E
A
N
P
K
A
Q
G
L
L
R
G
Rat
Rattus norvegicus
NP_001008329
526
58850
S451
H
I
T
M
D
D
P
S
L
K
S
P
P
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520908
193
21776
D127
R
Q
P
P
P
G
Y
D
S
V
I
A
R
G
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
P31669
998
111108
Q920
H
E
L
K
A
A
S
Q
I
T
K
L
P
K
G
Zebra Danio
Brachydanio rerio
NP_956795
531
59822
A459
P
S
L
R
K
A
P
A
G
Y
D
S
V
I
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785135
532
59769
N462
C
S
L
K
E
A
P
N
G
C
D
C
V
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O50017
653
72977
D577
E
L
L
N
A
D
Y
D
A
N
N
L
P
K
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q11207
637
72157
N562
E
L
L
Y
S
D
Y
N
A
D
N
L
P
P
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97
87.8
N.A.
N.A.
34.3
80.6
N.A.
27.9
N.A.
20.8
55.1
N.A.
N.A.
N.A.
N.A.
50.2
Protein Similarity:
100
98.3
89.4
N.A.
N.A.
52.4
86.8
N.A.
31.7
N.A.
33.4
72.9
N.A.
N.A.
N.A.
N.A.
65.6
P-Site Identity:
100
100
86.6
N.A.
N.A.
20
80
N.A.
0
N.A.
20
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
86.6
N.A.
N.A.
33.3
86.6
N.A.
0
N.A.
26.6
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
29.7
N.A.
31.2
N.A.
N.A.
Protein Similarity:
N.A.
46.5
N.A.
47.5
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
28
28
0
10
28
0
0
10
0
0
19
% A
% Cys:
10
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% C
% Asp:
0
0
0
0
37
28
0
19
0
10
19
0
0
0
0
% D
% Glu:
28
10
0
10
10
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
19
0
10
0
0
10
73
% G
% His:
46
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
37
0
0
0
0
0
0
10
0
10
0
0
19
0
% I
% Lys:
0
0
0
19
10
10
0
10
0
37
10
0
0
19
0
% K
% Leu:
0
28
55
0
0
0
0
0
37
0
0
37
10
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
19
10
0
28
0
19
0
10
19
0
0
0
0
% N
% Pro:
10
0
10
10
10
0
64
0
0
0
0
37
64
46
0
% P
% Gln:
0
10
0
0
0
0
0
10
0
10
0
0
0
0
10
% Q
% Arg:
10
0
0
10
0
0
0
0
0
0
0
0
10
10
0
% R
% Ser:
0
19
0
0
10
0
10
37
10
0
37
10
0
0
0
% S
% Thr:
0
0
19
28
0
0
0
0
0
10
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
0
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
28
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _