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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PARP3 All Species: 8.79
Human Site: T60 Identified Species: 19.33
UniProt: Q9Y6F1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6F1 NP_005476.3 533 60070 T60 P L S S N P G T Q V Y E D Y N
Chimpanzee Pan troglodytes XP_001170254 532 60080 T60 P L S S N P G T Q V Y E D Y D
Rhesus Macaque Macaca mulatta XP_001087761 503 56366 T60 P L S S N P E T Q V H E D Y D
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O88554 559 63378 C89 L G K A H V Y C E G D D V Y D
Rat Rattus norvegicus NP_001008329 526 58850 I58 P L S G N P G I Q V H E D Y D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520908 193 21776
Chicken Gallus gallus
Frog Xenopus laevis P31669 998 111108 E115 R S A C K G C E Q K I E K G Q
Zebra Danio Brachydanio rerio NP_956795 531 59822 A61 S V C H L S N A E V H E D Y D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785135 532 59769 G57 D S L C S W P G T V V D D Y D
Poplar Tree Populus trichocarpa
Maize Zea mays O50017 653 72977 Q184 K V N Y H V L Q V G D E I Y D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q11207 637 72157 Q163 K S Q Y H V L Q R G D D V Y D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97 87.8 N.A. N.A. 34.3 80.6 N.A. 27.9 N.A. 20.8 55.1 N.A. N.A. N.A. N.A. 50.2
Protein Similarity: 100 98.3 89.4 N.A. N.A. 52.4 86.8 N.A. 31.7 N.A. 33.4 72.9 N.A. N.A. N.A. N.A. 65.6
P-Site Identity: 100 93.3 80 N.A. N.A. 6.6 73.3 N.A. 0 N.A. 13.3 26.6 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 93.3 N.A. N.A. 40 86.6 N.A. 0 N.A. 20 53.3 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. 29.7 N.A. 31.2 N.A. N.A.
Protein Similarity: N.A. 46.5 N.A. 47.5 N.A. N.A.
P-Site Identity: N.A. 13.3 N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. 40 N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 0 0 0 10 0 0 0 0 0 0 0 % A
% Cys: 0 0 10 19 0 0 10 10 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 28 28 55 0 73 % D
% Glu: 0 0 0 0 0 0 10 10 19 0 0 64 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 10 0 10 28 10 0 28 0 0 0 10 0 % G
% His: 0 0 0 10 28 0 0 0 0 0 28 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 10 0 0 10 0 10 0 0 % I
% Lys: 19 0 10 0 10 0 0 0 0 10 0 0 10 0 0 % K
% Leu: 10 37 10 0 10 0 19 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 37 0 10 0 0 0 0 0 0 0 10 % N
% Pro: 37 0 0 0 0 37 10 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 10 0 0 0 0 19 46 0 0 0 0 0 10 % Q
% Arg: 10 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % R
% Ser: 10 28 37 28 10 10 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 28 10 0 0 0 0 0 0 % T
% Val: 0 19 0 0 0 28 0 0 10 55 10 0 19 0 0 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 19 0 0 10 0 0 0 19 0 0 82 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _