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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PARP3
All Species:
33.03
Human Site:
Y518
Identified Species:
72.67
UniProt:
Q9Y6F1
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6F1
NP_005476.3
533
60070
Y518
S
Q
S
E
Y
L
I
Y
Q
E
S
Q
C
R
L
Chimpanzee
Pan troglodytes
XP_001170254
532
60080
Y517
S
Q
S
E
Y
L
I
Y
Q
E
S
Q
C
R
L
Rhesus Macaque
Macaca mulatta
XP_001087761
503
56366
Y488
S
Q
S
E
Y
L
I
Y
Q
E
S
Q
C
R
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88554
559
63378
Y538
N
Y
N
E
F
I
V
Y
S
P
N
Q
V
R
M
Rat
Rattus norvegicus
NP_001008329
526
58850
Y511
S
Q
S
E
Y
L
I
Y
K
E
S
Q
C
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520908
193
21776
Q179
Q
S
E
Y
L
I
Y
Q
E
S
Q
C
R
I
R
Chicken
Gallus gallus
Frog
Xenopus laevis
P31669
998
111108
Y975
L
Y
N
E
Y
I
V
Y
D
I
A
Q
V
N
L
Zebra Danio
Brachydanio rerio
NP_956795
531
59822
Y513
Y
N
S
E
Y
L
I
Y
K
E
S
Q
C
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785135
532
59769
Y516
Y
Q
S
E
Y
L
V
Y
K
E
S
Q
N
R
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O50017
653
72977
Y633
L
Y
N
E
Y
I
V
Y
N
V
D
Q
I
R
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q11207
637
72157
Y618
L
Y
N
E
Y
I
V
Y
N
V
E
Q
I
K
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97
87.8
N.A.
N.A.
34.3
80.6
N.A.
27.9
N.A.
20.8
55.1
N.A.
N.A.
N.A.
N.A.
50.2
Protein Similarity:
100
98.3
89.4
N.A.
N.A.
52.4
86.8
N.A.
31.7
N.A.
33.4
72.9
N.A.
N.A.
N.A.
N.A.
65.6
P-Site Identity:
100
100
100
N.A.
N.A.
26.6
93.3
N.A.
0
N.A.
33.3
73.3
N.A.
N.A.
N.A.
N.A.
66.6
P-Site Similarity:
100
100
100
N.A.
N.A.
73.3
100
N.A.
13.3
N.A.
60
86.6
N.A.
N.A.
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
29.7
N.A.
31.2
N.A.
N.A.
Protein Similarity:
N.A.
46.5
N.A.
47.5
N.A.
N.A.
P-Site Identity:
N.A.
33.3
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
60
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
46
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% D
% Glu:
0
0
10
91
0
0
0
0
10
55
10
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
46
46
0
0
10
0
0
19
10
10
% I
% Lys:
0
0
0
0
0
0
0
0
28
0
0
0
0
10
0
% K
% Leu:
28
0
0
0
10
55
0
0
0
0
0
0
0
0
46
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
37
% M
% Asn:
10
10
37
0
0
0
0
0
19
0
10
0
10
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% P
% Gln:
10
46
0
0
0
0
0
10
28
0
10
91
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
10
73
10
% R
% Ser:
37
10
55
0
0
0
0
0
10
10
55
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
46
0
0
19
0
0
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
19
37
0
10
82
0
10
91
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _