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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WNT6
All Species:
20
Human Site:
S216
Identified Species:
44
UniProt:
Q9Y6F9
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6F9
NP_006513.1
365
39721
S216
A
G
R
L
A
V
R
S
H
T
R
T
E
C
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095541
365
39688
S216
A
G
R
L
A
V
R
S
H
T
R
T
E
C
K
Dog
Lupus familis
XP_545647
453
49432
S304
A
G
R
L
A
V
R
S
H
T
R
T
E
C
K
Cat
Felis silvestris
Mouse
Mus musculus
P22727
364
39568
S215
A
G
R
L
A
V
R
S
H
T
R
T
E
C
K
Rat
Rattus norvegicus
Q9QXQ5
351
39025
T200
A
G
R
K
A
I
L
T
H
M
R
V
E
C
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Q07DZ8
361
40096
R201
A
G
R
K
A
V
K
R
F
L
K
Q
E
C
K
Chicken
Gallus gallus
P49337
351
38945
N200
A
G
R
K
A
I
L
N
N
M
R
V
E
C
K
Frog
Xenopus laevis
P10108
371
41107
T212
A
G
R
L
T
V
L
T
E
M
R
Q
E
C
K
Zebra Danio
Brachydanio rerio
P47793
352
39413
N200
A
G
R
K
A
I
L
N
H
M
R
V
E
C
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396945
359
39626
E210
A
G
R
L
A
I
R
E
F
M
S
T
E
C
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790077
352
39690
K198
A
G
R
L
S
I
A
K
H
M
R
R
E
C
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.1
77.9
N.A.
97.2
43.5
N.A.
40.5
42.7
45
43.5
N.A.
N.A.
50.4
N.A.
51.7
Protein Similarity:
100
N.A.
99.4
78.8
N.A.
98.3
60.2
N.A.
56.4
60.5
60.1
60.2
N.A.
N.A.
68.2
N.A.
68.4
P-Site Identity:
100
N.A.
100
100
N.A.
100
60
N.A.
53.3
53.3
60
60
N.A.
N.A.
66.6
N.A.
60
P-Site Similarity:
100
N.A.
100
100
N.A.
100
73.3
N.A.
66.6
73.3
66.6
73.3
N.A.
N.A.
73.3
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
100
0
0
0
82
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
10
10
0
0
0
100
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
19
0
0
0
0
0
0
% F
% Gly:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
64
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
46
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
37
0
0
10
10
0
0
10
0
0
0
100
% K
% Leu:
0
0
0
64
0
0
37
0
0
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
55
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
19
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% Q
% Arg:
0
0
100
0
0
0
46
10
0
0
82
10
0
0
0
% R
% Ser:
0
0
0
0
10
0
0
37
0
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
10
0
0
19
0
37
0
46
0
0
0
% T
% Val:
0
0
0
0
0
55
0
0
0
0
0
28
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _