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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WNT6
All Species:
13.64
Human Site:
S258
Identified Species:
30
UniProt:
Q9Y6F9
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6F9
NP_006513.1
365
39721
S258
L
E
R
F
H
G
A
S
R
V
M
G
T
N
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095541
365
39688
S258
L
E
R
F
H
G
A
S
R
V
M
G
T
N
D
Dog
Lupus familis
XP_545647
453
49432
S346
L
E
R
F
H
G
A
S
R
V
M
G
T
N
D
Cat
Felis silvestris
Mouse
Mus musculus
P22727
364
39568
S257
L
E
R
F
H
G
A
S
R
V
M
G
T
N
D
Rat
Rattus norvegicus
Q9QXQ5
351
39025
V244
K
F
D
G
A
T
E
V
E
P
R
R
V
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Q07DZ8
361
40096
I243
W
R
K
Y
N
G
A
I
Q
V
V
M
N
Q
D
Chicken
Gallus gallus
P49337
351
38945
V244
K
F
D
G
A
T
E
V
E
Q
S
E
I
G
S
Frog
Xenopus laevis
P10108
371
41107
N264
T
Y
S
N
N
G
S
N
R
W
G
S
R
S
D
Zebra Danio
Brachydanio rerio
P47793
352
39413
E245
F
D
G
A
T
E
V
E
L
R
K
V
G
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396945
359
39626
A252
K
E
S
F
D
G
A
A
K
V
I
P
S
N
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790077
352
39690
V240
K
S
Y
F
D
G
A
V
K
V
T
G
G
N
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.1
77.9
N.A.
97.2
43.5
N.A.
40.5
42.7
45
43.5
N.A.
N.A.
50.4
N.A.
51.7
Protein Similarity:
100
N.A.
99.4
78.8
N.A.
98.3
60.2
N.A.
56.4
60.5
60.1
60.2
N.A.
N.A.
68.2
N.A.
68.4
P-Site Identity:
100
N.A.
100
100
N.A.
100
0
N.A.
26.6
0
20
0
N.A.
N.A.
46.6
N.A.
40
P-Site Similarity:
100
N.A.
100
100
N.A.
100
0
N.A.
60
0
46.6
6.6
N.A.
N.A.
73.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
19
0
64
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
19
0
19
0
0
0
0
0
0
0
0
0
64
% D
% Glu:
0
46
0
0
0
10
19
10
19
0
0
10
0
0
0
% E
% Phe:
10
19
0
55
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
19
0
73
0
0
0
0
10
46
19
19
0
% G
% His:
0
0
0
0
37
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
10
0
10
0
0
% I
% Lys:
37
0
10
0
0
0
0
0
19
0
10
0
0
0
0
% K
% Leu:
37
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
37
10
0
0
0
% M
% Asn:
0
0
0
10
19
0
0
10
0
0
0
0
10
55
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
10
0
0
0
10
0
% Q
% Arg:
0
10
37
0
0
0
0
0
46
10
10
10
10
0
0
% R
% Ser:
0
10
19
0
0
0
10
37
0
0
10
10
10
10
28
% S
% Thr:
10
0
0
0
10
19
0
0
0
0
10
0
37
10
10
% T
% Val:
0
0
0
0
0
0
10
28
0
64
10
10
10
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
10
10
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _