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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM14A All Species: 26.97
Human Site: S47 Identified Species: 53.94
UniProt: Q9Y6G1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6G1 NP_054770.1 99 10712 S47 G Y G A Y R V S N D K R D V K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001107829 87 9356 A39 G L F V G C L A G Y G A Y R V
Dog Lupus familis XP_532172 204 21523 S152 G Y G A Y R V S N D K R D V K
Cat Felis silvestris
Mouse Mus musculus P56983 99 10575 S47 G Y G A Y R V S N D R R D V K
Rat Rattus norvegicus Q924P2 115 11757 S57 G L G A Y Q L S Q D P R N V W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516532 101 10853 S49 T Y G A F C V S R D T R D V K
Chicken Gallus gallus
Frog Xenopus laevis NP_001085989 101 10721 S49 G Y G A Y R V S S D P T D I K
Zebra Danio Brachydanio rerio Q0P436 107 10663 S49 G F G A Y Q T S Q D P G N I W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W1K0 112 11563 S49 G Y G A H L N S Q D T P R P L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795741 101 10475 S48 G Y G A S L T S K N P N D F F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O64847 108 11090 G53 Y V Y T E L P G N P V L A S S
Baker's Yeast Sacchar. cerevisiae P47131 105 11232 H47 G I A G Y L L H M N R D G G L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 86.8 46 N.A. 92.9 49.5 N.A. 70.3 N.A. 62.3 48.5 N.A. 41 N.A. N.A. 47.5
Protein Similarity: 100 N.A. 86.8 47.5 N.A. 95.9 62.6 N.A. 82.1 N.A. 75.2 62.6 N.A. 54.4 N.A. N.A. 60.4
P-Site Identity: 100 N.A. 6.6 100 N.A. 93.3 53.3 N.A. 66.6 N.A. 73.3 40 N.A. 40 N.A. N.A. 40
P-Site Similarity: 100 N.A. 20 100 N.A. 100 73.3 N.A. 73.3 N.A. 86.6 66.6 N.A. 46.6 N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. 32.4 24.7 N.A.
Protein Similarity: N.A. N.A. N.A. 50.9 47.6 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 75 0 0 0 9 0 0 0 9 9 0 0 % A
% Cys: 0 0 0 0 0 17 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 67 0 9 50 0 0 % D
% Glu: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 9 9 0 9 0 0 0 0 0 0 0 0 9 9 % F
% Gly: 84 0 75 9 9 0 0 9 9 0 9 9 9 9 0 % G
% His: 0 0 0 0 9 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 9 0 0 0 0 0 0 0 0 0 0 0 17 0 % I
% Lys: 0 0 0 0 0 0 0 0 9 0 17 0 0 0 42 % K
% Leu: 0 17 0 0 0 34 25 0 0 0 0 9 0 0 17 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 9 0 34 17 0 9 17 0 0 % N
% Pro: 0 0 0 0 0 0 9 0 0 9 34 9 0 9 0 % P
% Gln: 0 0 0 0 0 17 0 0 25 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 34 0 0 9 0 17 42 9 9 0 % R
% Ser: 0 0 0 0 9 0 0 75 9 0 0 0 0 9 9 % S
% Thr: 9 0 0 9 0 0 17 0 0 0 17 9 0 0 0 % T
% Val: 0 9 0 9 0 0 42 0 0 0 9 0 0 42 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 % W
% Tyr: 9 59 9 0 59 0 0 0 0 9 0 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _