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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM14A
All Species:
35.15
Human Site:
S74
Identified Species:
70.3
UniProt:
Q9Y6G1
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6G1
NP_054770.1
99
10712
S74
M
G
V
R
F
K
R
S
K
K
I
M
P
A
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001107829
87
9356
I66
T
A
F
F
L
A
T
I
M
G
V
R
F
K
R
Dog
Lupus familis
XP_532172
204
21523
S179
M
G
V
R
Y
K
R
S
K
K
I
M
P
A
G
Cat
Felis silvestris
Mouse
Mus musculus
P56983
99
10575
S74
M
G
V
R
F
K
R
S
K
K
V
M
P
A
G
Rat
Rattus norvegicus
Q924P2
115
11757
S84
M
G
M
R
F
Y
N
S
G
K
F
M
P
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516532
101
10853
S76
M
G
V
R
F
K
R
S
K
K
L
M
P
A
G
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085989
101
10721
S76
M
G
L
R
Y
N
R
S
R
K
I
M
P
A
G
Zebra Danio
Brachydanio rerio
Q0P436
107
10663
S76
M
G
K
R
F
Y
N
S
R
K
I
T
P
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1K0
112
11563
S76
M
G
A
R
W
N
R
S
G
K
L
M
P
A
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795741
101
10475
S75
M
G
Y
R
F
S
N
S
G
K
F
M
P
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O64847
108
11090
T80
M
G
S
R
Y
L
R
T
R
K
V
V
P
A
G
Baker's Yeast
Sacchar. cerevisiae
P47131
105
11232
P74
A
G
V
I
R
G
M
P
S
R
F
T
K
P
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
86.8
46
N.A.
92.9
49.5
N.A.
70.3
N.A.
62.3
48.5
N.A.
41
N.A.
N.A.
47.5
Protein Similarity:
100
N.A.
86.8
47.5
N.A.
95.9
62.6
N.A.
82.1
N.A.
75.2
62.6
N.A.
54.4
N.A.
N.A.
60.4
P-Site Identity:
100
N.A.
0
93.3
N.A.
93.3
66.6
N.A.
93.3
N.A.
73.3
66.6
N.A.
66.6
N.A.
N.A.
66.6
P-Site Similarity:
100
N.A.
6.6
100
N.A.
100
73.3
N.A.
100
N.A.
93.3
73.3
N.A.
80
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.4
24.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.9
47.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
9
0
0
9
0
0
0
0
0
0
0
84
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
9
9
50
0
0
0
0
0
25
0
9
0
0
% F
% Gly:
0
92
0
0
0
9
0
0
25
9
0
0
0
0
84
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
9
0
0
34
0
0
0
0
% I
% Lys:
0
0
9
0
0
34
0
0
34
84
0
0
9
9
0
% K
% Leu:
0
0
9
0
9
9
0
0
0
0
17
0
0
0
0
% L
% Met:
84
0
9
0
0
0
9
0
9
0
0
67
0
0
0
% M
% Asn:
0
0
0
0
0
17
25
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
9
0
0
0
0
84
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
84
9
0
59
0
25
9
0
9
0
0
9
% R
% Ser:
0
0
9
0
0
9
0
75
9
0
0
0
0
0
0
% S
% Thr:
9
0
0
0
0
0
9
9
0
0
0
17
0
0
0
% T
% Val:
0
0
42
0
0
0
0
0
0
0
25
9
0
0
9
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
25
17
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _