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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM14A
All Species:
24.85
Human Site:
Y20
Identified Species:
49.7
UniProt:
Q9Y6G1
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6G1
NP_054770.1
99
10712
Y20
T
F
G
S
I
F
G
Y
K
R
R
G
G
V
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001107829
87
9356
V12
G
F
G
Y
A
A
L
V
T
F
G
S
I
F
G
Dog
Lupus familis
XP_532172
204
21523
Y125
T
F
G
S
I
L
G
Y
K
R
R
G
G
L
P
Cat
Felis silvestris
Mouse
Mus musculus
P56983
99
10575
Y20
T
I
G
S
V
L
G
Y
K
R
R
G
G
V
P
Rat
Rattus norvegicus
Q924P2
115
11757
Y30
A
T
G
G
I
I
G
Y
A
K
A
G
S
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516532
101
10853
Y22
A
F
G
G
V
L
G
Y
N
R
K
G
S
I
I
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085989
101
10721
Y22
A
V
G
G
Y
M
G
Y
S
R
K
G
S
I
V
Zebra Danio
Brachydanio rerio
Q0P436
107
10663
Y22
A
S
G
G
V
I
G
Y
V
K
A
G
S
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1K0
112
11563
Y22
A
A
G
G
I
M
G
Y
A
K
A
G
S
I
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795741
101
10475
Y21
A
I
G
G
A
M
G
Y
L
K
A
G
S
T
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O64847
108
11090
L26
V
G
G
L
M
G
Y
L
K
R
G
S
K
I
S
Baker's Yeast
Sacchar. cerevisiae
P47131
105
11232
Y20
T
A
G
G
L
M
G
Y
Y
R
K
G
S
I
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
86.8
46
N.A.
92.9
49.5
N.A.
70.3
N.A.
62.3
48.5
N.A.
41
N.A.
N.A.
47.5
Protein Similarity:
100
N.A.
86.8
47.5
N.A.
95.9
62.6
N.A.
82.1
N.A.
75.2
62.6
N.A.
54.4
N.A.
N.A.
60.4
P-Site Identity:
100
N.A.
13.3
86.6
N.A.
80
46.6
N.A.
40
N.A.
33.3
40
N.A.
40
N.A.
N.A.
26.6
P-Site Similarity:
100
N.A.
13.3
93.3
N.A.
86.6
53.3
N.A.
60
N.A.
46.6
53.3
N.A.
53.3
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.4
24.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.9
47.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
17
0
0
17
9
0
0
17
0
34
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
34
0
0
0
9
0
0
0
9
0
0
0
9
0
% F
% Gly:
9
9
100
59
0
9
84
0
0
0
17
84
25
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
17
0
0
34
17
0
0
0
0
0
0
9
42
9
% I
% Lys:
0
0
0
0
0
0
0
0
34
34
25
0
9
0
0
% K
% Leu:
0
0
0
9
9
25
9
9
9
0
0
0
0
9
0
% L
% Met:
0
0
0
0
9
34
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
59
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
59
25
0
0
0
0
% R
% Ser:
0
9
0
25
0
0
0
0
9
0
0
17
59
0
9
% S
% Thr:
34
9
0
0
0
0
0
0
9
0
0
0
0
9
0
% T
% Val:
9
9
0
0
25
0
0
9
9
0
0
0
0
34
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
9
0
9
84
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _