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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XRCC6BP1 All Species: 19.09
Human Site: T227 Identified Species: 38.18
UniProt: Q9Y6H3 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6H3 NP_150592.1 246 28081 T227 G R I P H N K T Y A R Y A H R
Chimpanzee Pan troglodytes XP_509179 342 38131 T323 G R I P H N K T Y A R Y A H R
Rhesus Macaque Macaca mulatta XP_001102089 269 30431 T250 G R I P H N K T Y A R Y A H R
Dog Lupus familis XP_531653 267 30310 T248 G R I P H N K T Y A R Y A H R
Cat Felis silvestris
Mouse Mus musculus Q9CWQ3 201 21691 S183 Q H H Q I E T S C V S R P A M
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518485 178 20461 D160 R I P H G K K D A R F A Y R D
Chicken Gallus gallus XP_416054 242 27514 T223 G R I P H S K T D A K R A Y K
Frog Xenopus laevis Q7T0P7 235 26883 A216 G R I P H S K A D A K F A Y R
Zebra Danio Brachydanio rerio A4IGF3 254 28965 K235 G R I P H S K K D A K F A H R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609845 283 31854 S265 G R R I R R N S T D Q Q K A Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783122 198 22286 K180 P R R L A D L K T S S H D Q S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53722 227 26872 I207 S K E H A A K I V D E V W D S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71 81.7 78.6 N.A. 59.7 N.A. N.A. 56.9 63.8 67 63.7 N.A. 33.5 N.A. N.A. 40.2
Protein Similarity: 100 71.6 83.2 84.2 N.A. 67.4 N.A. N.A. 65.8 77.2 79.6 75.9 N.A. 51.9 N.A. N.A. 56.5
P-Site Identity: 100 100 100 100 N.A. 0 N.A. N.A. 6.6 60 60 66.6 N.A. 13.3 N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 6.6 N.A. N.A. 6.6 86.6 86.6 86.6 N.A. 26.6 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 17 9 0 9 9 59 0 9 59 17 0 % A
% Cys: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 9 0 9 25 17 0 0 9 9 9 % D
% Glu: 0 0 9 0 0 9 0 0 0 0 9 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 9 17 0 0 0 % F
% Gly: 67 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 9 9 17 59 0 0 0 0 0 0 9 0 42 0 % H
% Ile: 0 9 59 9 9 0 0 9 0 0 0 0 0 0 0 % I
% Lys: 0 9 0 0 0 9 75 17 0 0 25 0 9 0 9 % K
% Leu: 0 0 0 9 0 0 9 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 0 0 0 0 0 34 9 0 0 0 0 0 0 0 0 % N
% Pro: 9 0 9 59 0 0 0 0 0 0 0 0 9 0 0 % P
% Gln: 9 0 0 9 0 0 0 0 0 0 9 9 0 9 0 % Q
% Arg: 9 75 17 0 9 9 0 0 0 9 34 17 0 9 50 % R
% Ser: 9 0 0 0 0 25 0 17 0 9 17 0 0 0 17 % S
% Thr: 0 0 0 0 0 0 9 42 17 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 9 9 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 34 0 0 34 9 17 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _