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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EPN1 All Species: 23.03
Human Site: S395 Identified Species: 50.67
UniProt: Q9Y6I3 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6I3 NP_001123543.1 551 57575 S395 A L P T S G S S A G E L E L L
Chimpanzee Pan troglodytes XP_001136868 551 57647 S395 A L P T S G S S A G E L E L L
Rhesus Macaque Macaca mulatta XP_001089973 551 57588 S395 A L P T S G S S A G E L E L L
Dog Lupus familis XP_862214 544 57009 S388 A L P T S G S S T G E L E L L
Cat Felis silvestris
Mouse Mus musculus Q80VP1 575 60194 S419 A L P T S G S S T G E L E L L
Rat Rattus norvegicus O88339 575 60140 S419 A L P T S G S S T G E L E L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507706 601 64482 Q439 S A S S L P S Q N N G T T S P
Chicken Gallus gallus NP_001012806 483 52552 P334 S V D P W A A P A G S A T Q S
Frog Xenopus laevis NP_001081892 609 64571 T434 P D A F D M S T M S G S L C D
Zebra Danio Brachydanio rerio XP_686465 582 61932 S428 P T R K T P E S F L G P N A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P47160 408 45073 E259 K E L I Q E D E K K A D E E E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99 93.8 N.A. 90.7 90.6 N.A. 43.9 39 51.8 37.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.6 99.4 94.7 N.A. 91.8 91.6 N.A. 54.7 50.6 59.9 50.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 6.6 13.3 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 20 33.3 13.3 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 38.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 55 10 10 0 0 10 10 0 37 0 10 10 0 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 10 10 0 10 0 10 0 0 0 0 10 0 0 10 % D
% Glu: 0 10 0 0 0 10 10 10 0 0 55 0 64 10 10 % E
% Phe: 0 0 0 10 0 0 0 0 10 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 55 0 0 0 64 28 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 10 0 0 0 0 10 10 0 0 0 0 0 % K
% Leu: 0 55 10 0 10 0 0 0 0 10 0 55 10 55 55 % L
% Met: 0 0 0 0 0 10 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 10 10 0 0 10 0 0 % N
% Pro: 19 0 55 10 0 19 0 10 0 0 0 10 0 0 10 % P
% Gln: 0 0 0 0 10 0 0 10 0 0 0 0 0 10 0 % Q
% Arg: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 19 0 10 10 55 0 73 64 0 10 10 10 0 10 10 % S
% Thr: 0 10 0 55 10 0 0 10 28 0 0 10 19 0 0 % T
% Val: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _