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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP3
All Species:
16.06
Human Site:
S296
Identified Species:
27.18
UniProt:
Q9Y6I4
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6I4
NP_006528.2
520
58897
S296
L
Q
E
N
S
T
L
S
A
S
N
K
C
C
I
Chimpanzee
Pan troglodytes
XP_510466
498
56646
S285
K
C
C
I
N
G
A
S
T
V
V
T
A
I
F
Rhesus Macaque
Macaca mulatta
XP_001105997
520
58882
S296
L
Q
E
N
S
T
L
S
A
S
N
K
C
C
I
Dog
Lupus familis
XP_544715
435
49586
S222
K
C
C
I
N
G
A
S
T
V
V
T
A
I
F
Cat
Felis silvestris
Mouse
Mus musculus
Q91W36
520
58850
S296
L
Q
E
N
S
T
L
S
A
S
N
K
C
C
I
Rat
Rattus norvegicus
B2GUX4
565
62681
S350
L
H
E
E
P
E
L
S
D
D
D
R
A
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O57429
357
40913
P143
A
D
T
L
D
H
L
P
D
D
E
K
S
R
Q
Frog
Xenopus laevis
Q6DCJ1
523
60090
I294
N
P
N
H
C
N
C
I
I
D
Q
I
F
T
G
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
T291
G
G
L
Q
S
D
V
T
C
Q
V
C
H
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR1
735
82440
N520
S
G
S
G
S
G
T
N
S
S
N
S
S
S
S
Honey Bee
Apis mellifera
XP_392160
541
61414
L317
L
L
Q
L
L
P
R
L
G
H
E
P
L
G
L
Nematode Worm
Caenorhab. elegans
NP_493434
699
79496
S400
L
Q
A
L
A
S
I
S
E
F
R
E
Y
I
M
Sea Urchin
Strong. purpuratus
XP_781718
499
56662
F286
A
T
I
V
S
V
I
F
G
G
L
L
L
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
P258
Q
S
Y
V
L
D
L
P
N
A
K
E
V
S
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.4
99.2
82.3
N.A.
96.5
26
N.A.
N.A.
27.6
27.7
27.8
N.A.
22.9
41.5
23.4
53.4
Protein Similarity:
100
95
99.6
83
N.A.
98.8
39.2
N.A.
N.A.
41.3
43.2
44
N.A.
39.8
58.2
36.4
69
P-Site Identity:
100
6.6
100
6.6
N.A.
100
26.6
N.A.
N.A.
13.3
0
6.6
N.A.
20
6.6
20
6.6
P-Site Similarity:
100
13.3
100
13.3
N.A.
100
46.6
N.A.
N.A.
13.3
6.6
26.6
N.A.
33.3
20
53.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
8
0
8
0
15
0
22
8
0
0
22
0
0
% A
% Cys:
0
15
15
0
8
0
8
0
8
0
0
8
22
22
0
% C
% Asp:
0
8
0
0
8
15
0
0
15
22
8
0
0
0
0
% D
% Glu:
0
0
29
8
0
8
0
0
8
0
15
15
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
8
0
8
0
0
8
0
15
% F
% Gly:
8
15
0
8
0
22
0
0
15
8
0
0
0
15
8
% G
% His:
0
8
0
8
0
8
0
0
0
8
0
0
8
0
0
% H
% Ile:
0
0
8
15
0
0
15
8
8
0
0
8
0
22
22
% I
% Lys:
15
0
0
0
0
0
0
0
0
0
8
29
0
0
0
% K
% Leu:
43
8
8
22
15
0
43
8
0
0
8
8
15
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
0
8
22
15
8
0
8
8
0
29
0
0
8
0
% N
% Pro:
0
8
0
0
8
8
0
15
0
0
0
8
0
0
0
% P
% Gln:
8
29
8
8
0
0
0
0
0
8
8
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
8
8
0
8
8
% R
% Ser:
8
8
8
0
43
8
0
50
8
29
0
8
15
22
8
% S
% Thr:
0
8
8
0
0
22
8
8
15
0
0
15
0
8
0
% T
% Val:
0
0
0
15
0
8
8
0
0
15
22
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _