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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP3 All Species: 12.12
Human Site: T489 Identified Species: 20.51
UniProt: Q9Y6I4 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6I4 NP_006528.2 520 58897 T489 W F H F N D S T V T L T D E E
Chimpanzee Pan troglodytes XP_510466 498 56646 V468 F H F N D S T V T L T D E E T
Rhesus Macaque Macaca mulatta XP_001105997 520 58882 T489 W F H F N D S T V T L T D E E
Dog Lupus familis XP_544715 435 49586 V405 F H F N D S T V T L T D E D T
Cat Felis silvestris
Mouse Mus musculus Q91W36 520 58850 T489 W F H F N D S T V T V T D E E
Rat Rattus norvegicus B2GUX4 565 62681 D534 T G W H V Y N D S R V S P V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus O57429 357 40913 D327 S E W H S F N D S R V T P M S
Frog Xenopus laevis Q6DCJ1 523 60090 H485 Y T S F I R Q H K D Q W F K C
Zebra Danio Brachydanio rerio A6H8I0 506 58102 D476 K D Q W F K C D D A I I T K A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVR1 735 82440 D705 K D T W V K C D D H V I T M A
Honey Bee Apis mellifera XP_392160 541 61414 S511 W F H F N D S S V R P A T T D
Nematode Worm Caenorhab. elegans NP_493434 699 79496 W665 F G K R N G R W F Q F D D T V
Sea Urchin Strong. purpuratus XP_781718 499 56662 R469 V E E K V I T R C K A Y I L F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P50102 471 53605 K441 I S G G Q W F K F N D S M V S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.4 99.2 82.3 N.A. 96.5 26 N.A. N.A. 27.6 27.7 27.8 N.A. 22.9 41.5 23.4 53.4
Protein Similarity: 100 95 99.6 83 N.A. 98.8 39.2 N.A. N.A. 41.3 43.2 44 N.A. 39.8 58.2 36.4 69
P-Site Identity: 100 6.6 100 0 N.A. 93.3 0 N.A. N.A. 6.6 6.6 0 N.A. 0 53.3 13.3 0
P-Site Similarity: 100 33.3 100 33.3 N.A. 100 20 N.A. N.A. 26.6 20 20 N.A. 13.3 66.6 20 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 8 8 8 0 0 15 % A
% Cys: 0 0 0 0 0 0 15 0 8 0 0 0 0 0 8 % C
% Asp: 0 15 0 0 15 29 0 29 15 8 8 22 29 8 8 % D
% Glu: 0 15 8 0 0 0 0 0 0 0 0 0 15 29 22 % E
% Phe: 22 29 15 36 8 8 8 0 15 0 8 0 8 0 8 % F
% Gly: 0 15 8 8 0 8 0 0 0 0 0 0 0 0 0 % G
% His: 0 15 29 15 0 0 0 8 0 8 0 0 0 0 0 % H
% Ile: 8 0 0 0 8 8 0 0 0 0 8 15 8 0 0 % I
% Lys: 15 0 8 8 0 15 0 8 8 8 0 0 0 15 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 15 15 0 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 15 0 % M
% Asn: 0 0 0 15 36 0 15 0 0 8 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 8 0 15 0 0 % P
% Gln: 0 0 8 0 8 0 8 0 0 8 8 0 0 0 0 % Q
% Arg: 0 0 0 8 0 8 8 8 0 22 0 0 0 0 0 % R
% Ser: 8 8 8 0 8 15 29 8 15 0 0 15 0 0 22 % S
% Thr: 8 8 8 0 0 0 22 22 15 22 15 29 22 15 15 % T
% Val: 8 0 0 0 22 0 0 15 29 0 29 0 0 15 8 % V
% Trp: 29 0 15 15 0 8 0 8 0 0 0 8 0 0 0 % W
% Tyr: 8 0 0 0 0 8 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _