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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP3
All Species:
9.09
Human Site:
Y267
Identified Species:
15.38
UniProt:
Q9Y6I4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6I4
NP_006528.2
520
58897
Y267
D
A
H
E
F
M
R
Y
L
L
D
H
L
H
L
Chimpanzee
Pan troglodytes
XP_510466
498
56646
F258
H
L
E
L
Q
G
G
F
N
G
V
S
R
S
A
Rhesus Macaque
Macaca mulatta
XP_001105997
520
58882
Y267
D
A
H
E
F
M
R
Y
L
L
D
H
L
H
L
Dog
Lupus familis
XP_544715
435
49586
F195
H
L
E
L
Q
G
G
F
N
G
V
S
R
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q91W36
520
58850
Y267
D
A
H
E
F
M
R
Y
L
L
D
H
L
H
L
Rat
Rattus norvegicus
B2GUX4
565
62681
R320
L
H
L
E
I
N
R
R
G
R
R
A
P
P
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O57429
357
40913
F116
D
A
Q
E
F
L
R
F
L
L
D
G
L
H
G
Frog
Xenopus laevis
Q6DCJ1
523
60090
A267
D
A
H
E
F
L
I
A
A
L
D
V
L
H
R
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
N264
H
R
H
C
K
D
D
N
G
K
K
A
N
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR1
735
82440
A490
D
A
H
E
F
F
I
A
T
L
D
V
L
H
R
Honey Bee
Apis mellifera
XP_392160
541
61414
F277
A
I
S
P
E
C
L
F
L
V
I
W
K
V
V
Nematode Worm
Caenorhab. elegans
NP_493434
699
79496
G328
K
K
K
R
G
K
K
G
K
V
S
P
M
F
V
Sea Urchin
Strong. purpuratus
XP_781718
499
56662
H259
R
Y
L
L
D
R
L
H
T
E
L
Q
G
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
A231
W
K
I
N
Q
N
L
A
G
Y
S
Q
Q
D
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.4
99.2
82.3
N.A.
96.5
26
N.A.
N.A.
27.6
27.7
27.8
N.A.
22.9
41.5
23.4
53.4
Protein Similarity:
100
95
99.6
83
N.A.
98.8
39.2
N.A.
N.A.
41.3
43.2
44
N.A.
39.8
58.2
36.4
69
P-Site Identity:
100
0
100
0
N.A.
100
13.3
N.A.
N.A.
66.6
60
6.6
N.A.
60
6.6
0
0
P-Site Similarity:
100
6.6
100
6.6
N.A.
100
20
N.A.
N.A.
80
66.6
13.3
N.A.
60
26.6
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
43
0
0
0
0
0
22
8
0
0
15
0
0
22
% A
% Cys:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
43
0
0
0
8
8
8
0
0
0
43
0
0
8
0
% D
% Glu:
0
0
15
50
8
0
0
0
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
43
8
0
29
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
8
15
15
8
22
15
0
8
8
0
8
% G
% His:
22
8
43
0
0
0
0
8
0
0
0
22
0
43
0
% H
% Ile:
0
8
8
0
8
0
15
0
0
0
8
0
0
0
8
% I
% Lys:
8
15
8
0
8
8
8
0
8
8
8
0
8
0
0
% K
% Leu:
8
15
15
22
0
15
22
0
36
43
8
0
43
0
22
% L
% Met:
0
0
0
0
0
22
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
8
0
15
0
8
15
0
0
0
8
8
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
8
8
8
8
% P
% Gln:
0
0
8
0
22
0
0
0
0
0
0
15
8
0
0
% Q
% Arg:
8
8
0
8
0
8
36
8
0
8
8
0
15
0
15
% R
% Ser:
0
0
8
0
0
0
0
0
0
0
15
15
0
22
0
% S
% Thr:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
8
% T
% Val:
0
0
0
0
0
0
0
0
0
15
15
15
0
8
15
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
22
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _