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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP3
All Species:
10.91
Human Site:
Y419
Identified Species:
18.46
UniProt:
Q9Y6I4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6I4
NP_006528.2
520
58897
Y419
K
R
F
H
W
T
A
Y
L
R
N
K
V
D
T
Chimpanzee
Pan troglodytes
XP_510466
498
56646
L398
R
F
H
W
T
A
Y
L
R
N
K
V
D
T
Y
Rhesus Macaque
Macaca mulatta
XP_001105997
520
58882
Y419
K
R
F
H
W
T
A
Y
L
R
N
K
V
D
T
Dog
Lupus familis
XP_544715
435
49586
L335
R
F
H
W
T
A
Y
L
R
N
K
V
D
T
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q91W36
520
58850
Y419
K
R
F
H
W
T
A
Y
L
R
N
K
V
D
T
Rat
Rattus norvegicus
B2GUX4
565
62681
N464
R
I
L
V
L
H
L
N
R
F
S
T
S
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O57429
357
40913
F257
L
V
L
H
L
K
R
F
S
E
A
R
I
R
A
Frog
Xenopus laevis
Q6DCJ1
523
60090
K415
K
R
F
E
H
S
A
K
L
R
R
K
I
T
T
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
Y406
L
R
R
K
I
T
T
Y
V
S
F
P
L
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR1
735
82440
F635
V
S
F
H
L
K
R
F
E
H
S
A
L
I
D
Honey Bee
Apis mellifera
XP_392160
541
61414
K441
W
C
N
S
Y
R
S
K
V
D
T
Q
V
D
F
Nematode Worm
Caenorhab. elegans
NP_493434
699
79496
L595
I
R
K
L
P
Q
V
L
C
L
H
M
K
R
F
Sea Urchin
Strong. purpuratus
XP_781718
499
56662
V399
R
T
K
I
D
T
Y
V
Q
F
P
M
K
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
G371
R
F
E
H
L
L
N
G
S
N
R
K
L
D
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.4
99.2
82.3
N.A.
96.5
26
N.A.
N.A.
27.6
27.7
27.8
N.A.
22.9
41.5
23.4
53.4
Protein Similarity:
100
95
99.6
83
N.A.
98.8
39.2
N.A.
N.A.
41.3
43.2
44
N.A.
39.8
58.2
36.4
69
P-Site Identity:
100
0
100
0
N.A.
100
0
N.A.
N.A.
6.6
53.3
20
N.A.
13.3
13.3
6.6
6.6
P-Site Similarity:
100
6.6
100
6.6
N.A.
100
13.3
N.A.
N.A.
26.6
66.6
40
N.A.
33.3
40
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
15
29
0
0
0
8
8
0
0
8
% A
% Cys:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
8
0
0
15
36
15
% D
% Glu:
0
0
8
8
0
0
0
0
8
8
0
0
0
8
0
% E
% Phe:
0
22
36
0
0
0
0
15
0
15
8
0
0
0
15
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
8
% G
% His:
0
0
15
43
8
8
0
0
0
8
8
0
0
0
0
% H
% Ile:
8
8
0
8
8
0
0
0
0
0
0
0
15
8
0
% I
% Lys:
29
0
15
8
0
15
0
15
0
0
15
36
15
0
0
% K
% Leu:
15
0
15
8
29
8
8
22
29
8
0
0
22
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% M
% Asn:
0
0
8
0
0
0
8
8
0
22
22
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
8
8
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
8
0
0
8
0
0
0
% Q
% Arg:
36
43
8
0
0
8
15
0
22
29
15
8
0
22
0
% R
% Ser:
0
8
0
8
0
8
8
0
15
8
15
0
8
0
0
% S
% Thr:
0
8
0
0
15
36
8
0
0
0
8
8
0
22
29
% T
% Val:
8
8
0
8
0
0
8
8
15
0
0
15
29
0
0
% V
% Trp:
8
0
0
15
22
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
22
29
0
0
0
0
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _